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Table 4. One-Way Sensitivity Analyses for a Cost-Effectiveness Analysis of Treatment Strategies for Acute Otitis Media: 7 to 10 Days of Amoxicillin Compared With Delayed Prescription
Variable Variable Range Effect on ICUR

Amoxicillin cost, $ 7.74–14.95 54,200–68,000
Non–health care cost, $ 7.54–30.16 54,500–62,200
Office consultation cost, $ 17.12–68.46 43,300–85,600
Work loss cost, $ 46–182 58,100–56,000
Probability of clinical failure—routine amoxicillin 0.044–0.078 42,000–80,300
Probability of GI adverse effects from antibiotic 0.042–0.156 49,200–68,900
Probability of nonattendance—routine amoxicillin 0–0.076 71,600–53,600
Probability of nonattendance—DP 0–0.448 Dominant* if probability is <0.23; 33,000–89,400 if probability is >0.23
Probability of prescription redemption—DP 0.172–0.308 142,000–33,000
Utility of a day of treatment failure 0.646–0.794 40,500–98,600

ICUR = incremental cost utility ratio (cost-effectiveness ratio in dollars per quality-adjusted life-year); GI = gastrointestinal; DP = delayed prescription.
* Dominant: option was more effective and less costly than comparative option.





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