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1 Department of Primary Care & Social Medicine, Imperial College Faculty of Medicine, London, England
2 Wandsworth Primary Care Research Centre, Wandsworth Primary Care Trust, London, England
CORRESPONDING AUTHOR: Christopher Millett, PhD, FFPH Department of Primary Care & Social Medicine Imperial College Faculty of Medicine Reynolds Bldg St Dunstans Rd London W6 8RP, England c.millett{at}imperial.ac.uk
| ABSTRACT |
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METHODS We undertook a population-based, cross-sectional survey of medication prescriptions and blood pressure control among patients with hypertension using electronic medical records from 16 family practices in southwest London.
RESULTS Black patients with hypertension were significantly less likely to achieve an established treatment target for blood pressure control than white or South Asian patients (adjusted odds ratio, 0.86; 95% confidence interval, 0.74–0.99). The prevalence of cardiovascular comorbidities was higher among South Asian patients with hypertension than among their white or black counterparts (41.3% vs 28.5% vs 28.8%). The presence of 2 or more cardiovascular comorbidities was associated with significantly improved blood pressure control among white patients but not among black or South Asian patients (mean systolic blood pressure, –9.4 mm Hg, –0.6 mm Hg, and –1.8 mm Hg, respectively). South Asian patients with poorly controlled hypertension were prescribed fewer antihypertensive medications than their black or white peers (adjusted odds ratio, 0.66; 95% confidence interval, 0.46–0.96).
CONCLUSIONS Ethnic disparities in the management of hypertension have persisted in the United Kingdom despite major investment in quality improvement initiatives, including pay for performance. These disparities are particularly marked among patients with multiple cardiovascular conditions.
Key Words: Pay for performance hypertension disease management blood pressure ethnicity cardiovascular diseases comorbidities primary care practice-based research
| INTRODUCTION |
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Over the past decade, the UK government has implemented an ambitious quality improvement agenda, a key objective of which is to reduce disparities in the quality of chronic disease management.6 This agenda includes a series of National Service Frameworks for chronic conditions such as coronary heart disease, stroke, and diabetes, and the implementation of the Quality and Outcomes Framework as part of a new family practitioner contract in 2004. Described as the boldest attempt to link pay to performance in any health care system,7 the framework places considerable emphasis on improving the quality of care for individuals with cardiovascular disease.
Initiatives to improve the quality of health care, including pay-for-performance incentives, may produce unintended and undesirable consequences. For example, pay-for-performance incentives may worsen health disparities if quality improves more slowly among professionals serving ethnically diverse populations with a high disease burden.8
In this study, we examined ethnic disparities in the management of hypertension among individuals with and without cardiovascular comorbidities after the introduction of a major pay-for-performance program in the United Kingdom. Ethnic disparities in the quality of health care are a persistent feature in the country, despite a lack of financial barriers to accessing health care, universal health coverage, and numerous initiatives to reduce disparities.9 A clear conceptual framework for how disparities in quality of care and health care outcomes may arise is given in an overview by Arleen Brown and colleagues.10 Differences in the quality of care may arise through a number of mechanisms, including financial barriers, education, health-seeking behavior, and access to health services. In our study, we examined the end result of these mechanisms in a health care system offering universal health coverage to all segments of the population.
| METHODS |
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Hypertension is 1 of 19 areas within the clinical domain of the Quality and Outcomes Framework. Of the 83 points available for hypertension, 6 are assigned to the production of a registry of hypertensive patients, 20 are allocated to measurement of blood pressure in the previous 9 months (40%–90% of patients must achieve the target to obtain payment), and 57 are allocated to achieving a treatment target blood pressure of 150/90 mm Hg or less (40%–70% of patients must achieve the target to obtain payment). Blood pressure measurement in UK primary care is undertaken by family practitioners or practice nurses who enter values into electronic medical records.
Study Sample
The study was conducted in Wandsworth, southwest London, where residents are younger, more deprived, and more culturally diverse than is typical in England as a whole.11,12 The area covered by the study contained 16 primary care practices with a total registered population of 120,843 patients. Data for the present study were collected from these practices between November 2005 and January 2006. The study was approved by the Wandsworth Research Ethics Committee.
We identified all patients with essential hypertension using diagnostic Read codes in computerized family practice records. Read codes are the clinical classification system used in primary care in the United Kingdom.13 We then extracted clinical information, including information about cardiovascular comorbidities (coronary heart disease, heart failure, stroke, diabetes, and chronic renal failure), blood pressure values (the most recent reading), and currently prescribed antihypertensive medications. Patients reported their ethnic group to the family practices on the basis of the classifications that map to the 2001 UK census,12 either at registration or during a consultation at the practice. We categorized ethnicity into 3 groups (white, black, South Asian) for our analyses because numbers of patients in individual ethnic subgroups were small. A neighborhood socioeconomic status (SES) score was assigned to individual patients based on their postal code using the Index of Multiple Deprivation (IMD) 2004.11 This index is the most commonly used method of measuring neighborhood SES in the United Kingdom and is compiled from a variety of sources, including the 2001 UK census and unemployment and social security benefits records. Higher scores on this index indicate greater deprivation.
Data Analyses
For each ethnic group, we calculated mean systolic and diastolic blood pressure, and percentage of patients achieving an established treatment target (blood pressure <140/90 mm Hg) among patients with 0, 1, and 2 or more cardiovascular comorbidities. We calculated the number and type of antihypertensive medications prescribed in each group. Regression analysis was undertaken to examine associations between ethnicity, number of comorbidities, and blood pressure control, with age, sex, neighborhood SES score, and treatment (number of antihypertensive medications prescribed) as the independent variables. We used robust standard errors to take into account clustering of patients within general practices.14 Statistical analyses were performed using version 9.1 of Stata (Stata Corp, College Station, Texas).
| RESULTS |
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Women comprised a larger proportion of hypertensive patients without cardiovascular comorbidities than men (59.4% vs 40.6%), but this pattern was reversed among patients with 2 or more comorbidities (39.5% vs 60.5%) (Table 1
). Some 15.6% of the sample had diabetes, 12.3% had coronary heart disease, 3.1% had experienced a stroke, 2.7% had heart failure, and 1.5% had chronic renal failure. South Asian patients were more likely to have comorbidities than white or black patients (41.3% vs 28.5% vs 28.8%). Hypertensive black and South Asian patients with and without comorbidities were considerably younger than their white counterparts (Table 1
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Hypertensive patients with cardiovascular comorbidities were significantly more likely to meet the treatment target for blood pressure control than their peers without cardiovascular comorbidities (AOR, 1.79; 95% CI, 1.45–2.22). Associations between the presence of cardiovascular comorbidities and mean systolic blood pressure differed significantly between ethnic groups (P = .001) (Tables 2
and 3
). When white patients without comorbidity were the reference group, mean systolic blood pressure was significantly lower in white (–3.8 mm Hg) and South Asian (–5.1 mm Hg) patients with 1 cardiovascular comorbidity, and in white patients with 2 or more comorbidities (–9.4 mm Hg). In contrast, this improved control was not evident in black (–0.6 mm Hg) or South Asian patients (–1.8 mm Hg) with 2 more comorbidities. No interaction effect was evident for diastolic blood pressure (P = .27) or achievement of the treatment target for hypertension (P = .33).
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One in 5 patients (19.4%) with poorly controlled hypertension and a single cardiovascular comorbidity were prescribed 3 or more antihypertensive medications; the value was 27.2% in black, 13.1% in South Asian, and 21.3% in white patients (Table 5
). One in 3 patients (34.4%) with poorly controlled hypertension and multiple comorbidities were prescribed 3 or more antihypertensive medications; the value was lower in white patients (31.1%) and South Asian patients (28.6%) when compared with black patients (40.9%).
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| DISCUSSION |
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This population-based study is one of the few to examine disparities in the quality of hypertension management among individuals with cardiovascular comorbidities in a multiethnic population in the United Kingdom. All primary care practices within the study area participated in our survey. Our findings therefore provide a comprehensive and typical picture of the care provided in this ethnically diverse, urban location. The high percentage of patients having their ethnicity coded in practice records (94.8%) in this study is unique in a UK primary care setting. Combining what are known to be culturally and epidemiologically heterogeneous groups, that is, Indian, Pakistani, and Bangladeshi, into a South Asian group may have masked differences in associations seen between quality of care and number of comorbidities. Our sample may nonetheless have had insufficient power to detect an interaction effect between ethnicity, comorbidity, and mean diastolic blood pressure or achievement of the treatment target for hypertension.
Although our study provides an informative snapshot of current levels of care, use of cross-sectional data may introduce bias and does not permit us to determine whether there is a causal link between quality initiatives, such as pay for performance, and the variations in management of hypertension that we identified. More robust studies using longitudinal data with multiple measurement points and longer-term follow-up of patients are required to better evaluate the impact of these initiatives. We examined the relationship between cardiovascular comorbidities, rather than all comorbidities, and hypertension management in different ethnic groups. We cannot be sure that the associations found would apply to other common comorbidities, such as osteoarthritis or depression. The observed variations in blood pressure control may partly reflect variations in adherence to medications, which have been shown to systematically differ between the groups we studied.16 Finally, given the major differences between the UK and US health care systems, the findings may not all be transferable to the United States. For example, the United Kingdoms National Health Service provides universal coverage with access to primary care services free at the point of use. As a result, patients from ethnic minority groups in the United Kingdom, who are more likely to come from lower socioeconomic groups or to be unemployed, do not face financial barriers in accessing primary health care services.
Some previous US studies published on this issue suggest that the provision of health care to individuals with multiple conditions is of a similar quality to or better than that delivered to individuals with a single condition. For example, a study of more than 6,000 individuals with diabetes enrolled in a managed care organization found that quality of care did not vary with the presence of medical comorbidity, as measured by the Charlson Comorbidity Index.17 Higashi et al18 found that quality of care actually improved with an increasing number of conditions in 3 cohorts of community-dwelling adult patients. Both studies examined quality using process of care indicators across a larger number of conditions than examined here, including both cardiovascular and noncardiovascular comorbidities. These findings may reflect the fact that patients with multiple conditions have greater contact with health services. The results of our study suggest that this quality gain may extend to better control of intermediate clinical outcomes, such as blood pressure, which is in keeping with previous research on blood pressure control among patients with multiple cardiovascular comorbidities.19 Our findings also suggest, however, that this improved control may be restricted to white patients with comorbidities and does not extend to black and South Asian patients.
The number of people living with multiple cardiovascular conditions globally is high and set to increase,20,21 particularly in countries with aging populations and rapidly rising levels of obesity. This group represents a high priority for secondary prevention efforts given their increased likelihood of additional morbidity and mortality, and associated use of health care resources. Our findings suggest that the management of hypertension in ethnic minority groups remains suboptimal, particularly in individuals with cardiovascular comorbidities—despite a sustained period of investment in health care quality improvement in England and a health care system that offers universal access to services free at the point of use.
Policy makers and health care planners should consider the potential negative impacts of universal quality improvement programs, such as pay for performance, on health care disparities. Although such programs generally aim to improve overall levels of care, our findings suggest that additional efforts are required to improve the quality of care among high-risk individuals, including those from minority ethnic groups with multiple conditions. Such improvement could be facilitated by, for example, offering additional incentives to meet treatment targets in people who are from ethnic minority groups or who have multiple morbidities.
| ACKNOWLEDGMENTS |
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| FOOTNOTES |
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Funding support: This study represents independent research commissioned by the National Institute for Health Research. The Wandsworth Primary Care Research Centre has received funding from the Department of Health. We are grateful for support from the National Institute for Health Research Biomedical Research Centre Funding Scheme, and the Medical Research Council.
Disclaimer: The views expressed in this publication are those of the authors and not necessarily those of the National Health Service, the National Institute for Health Research, or the Department of Health.
Received for publication February 18, 2008. Revision received June 16, 2008. Accepted for publication June 24, 2008.
| REFERENCES |
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