Inward rectifier K + channels pass prominent inward currents, while outward currents are
largely blocked. The inward rectification is due to block by intracellular Mg 2+ and a Mg 2+ -…

Chronic kidney disease–mineral and bone disorder (CKD-MBD) is associated with secondary
hyperparathyroidism (HPT) and serum elevations in the phosphaturic hormone FGF23, …

Background The relationship between osteopathic manipulative treatment (OMT) and the
autonomic nervous system has long been acknowledged, but is poorly understood. In an effort …

Capsaicin, the active ingredient in some pain-relieving creams, is an agonist of a nonselective
cation channel known as the transient receptor potential vanilloid type 1 (TRPV1). The …

Objective To study effects of osteopathic manipulative treatment as an adjuvant therapy to
routine pediatric care in children with recurrent acute otitis media (AOM). Study Design …

Background. Calcitriol treatment of secondary hyperparathyroidism (HPT) in chronic kidney
disease (CKD) patients can lead to increased serum calcium and phosphorus, which have …

Developing mammals are more sensitive to noise, chemical and drug-induced ototoxicity
than adults, with maximum sensitivity occurring during periods of anatomical and functional …

This review critically evaluates the literature on aminoglycoside pharmacokinetics in order
to answer the question how fluid and tissue levels of the drugs relate to the development of …

Calcimimetics and vitamin D sterols reduce serum parathyroid hormone (PTH) in patients
with secondary hyperparathyroidism receiving dialysis, a disease state associated with …

Vascular calcification (VC) is frequently observed in patients with chronic renal failure and
appears to be an active process involving transdifferentiation of vascular smooth muscle cells (…