Dementia is characterized by a long preclinical phase that may last years to decades before
the onset of mild cognitive impairment. Slow gait speed and subjective memory complaint …

Objectives The issue of subjects with mild cognitive impairment (MCI) reverting to normal
cognition (NC) has to date been taken in limited consideration, and no conclusive data are …

Introduction Blood-based biomarkers of pathophysiological brain amyloid β (Aβ)
accumulation, particularly for preclinical target and large-scale interventions, are warranted …

Older adults show pronounced interindividual differences in terms of their technology
adoption, experiences and resources. To better understand this heterogeneity, we …

Research suggests that personality traits are associated with mild cognitive impairment
(MCI), dementia, and mortality risk, but the timing of when traits are most important in the …

Alzheimer's disease is the most common form of dementia and is a significant burden for
affected patients, carers, and health systems. Great advances have been made in …

Background: Differentiating mild cognitive impairment (MCI) from subjective cognitive
decline (SCD) is important because of the higher progression rate to dementia for MCI and …

Background Mild cognitive impairment (MCI) is often considered a transitional state between
normal and pathologic (eg, dementia) cognitive aging. Although its prognosis varies largely …

Background Mild cognitive impairment (MCI) is a neurocognitive state between normal
cognitive aging and dementia, with evidence of neuropsychological changes but insufficient …

Background: Cognitive impairment is a major problem in elderly, affecting quality of life. Pre-
clinical studies show that MMFS-01, a synapse density enhancer, is effective at reversing …