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Research ArticleOriginal Research

Discordance Between Drug Adherence as Reported by Patients and Drug Importance as Assessed by Physicians

Stéphanie Sidorkiewicz, Viet-Thi Tran, Cécile Cousyn, Elodie Perrodeau and Philippe Ravaud
The Annals of Family Medicine September 2016, 14 (5) 415-421; DOI: https://doi.org/10.1370/afm.1965
Stéphanie Sidorkiewicz
1Department of General Medicine, Paris Descartes University, Paris, France
2METHODS Team, INSERM U1153, Epidemiology and Statistics Sorbonne Paris Cité Research Centre, France
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Viet-Thi Tran
2METHODS Team, INSERM U1153, Epidemiology and Statistics Sorbonne Paris Cité Research Centre, France
3Department of General Medicine, Paris Diderot University, Paris, France
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  • For correspondence: thi.tran-viet@htd.aphp.fr
Cécile Cousyn
3Department of General Medicine, Paris Diderot University, Paris, France
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Elodie Perrodeau
2METHODS Team, INSERM U1153, Epidemiology and Statistics Sorbonne Paris Cité Research Centre, France
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Philippe Ravaud
2METHODS Team, INSERM U1153, Epidemiology and Statistics Sorbonne Paris Cité Research Centre, France
4French Cochrane Centre, Paris, France
5Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York
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Abstract

PURPOSE Among patients on long-term medical therapy, we compared (1) patient and physician assessments of drug adherence and of drug importance and (2) drug adherence reported by patients with drug importance as assessed by their physicians.

METHODS We recruited to the study patients receiving at least 1 long-term drug treatment from both hospital and ambulatory settings in France. We compared drug adherence reported by patients and drug importance assessed by physicians using Spearman correlation coefficients. Reasons for nonadherence were collected with open-ended questions and classified as intentional or unintentional.

RESULTS Between April and August 2014, we recruited 128 patients taking 498 drugs. Patients and physicians showed only weak agreement in their assessments of drug adherence (r = −0.25; 95% CI, −0.37 to −0.11) and drug importance (r = 0.07; 95% CI, 0.00 to 0.13). We did not find any correlation between physician-assessed drug importance and patient-reported drug adherence (r = −0.04; 95% CI, −0.14 to 0.06). In all, 94 (18.9%) of the drugs that physicians considered important were not correctly taken by patients. Patients intentionally did not adhere to 26 (48.1%) of the drugs for which they reported reasons for nonadherence.

CONCLUSIONS We found substantial discordance between patient and physician evaluations of drug adherence and drug importance. Nearly 20% of drugs considered important by physicians were not correctly taken by patients. These findings highlight the need for better patient-physician collaboration in drug treatment.

  • medication adherence
  • drug therapy
  • physician-patient relation
  • drug prescription
  • practice-based research
  • primary care
  • Received for publication December 22, 2015.
  • Revision received April 14, 2016.
  • Accepted for publication April 27, 2016.
  • © 2016 Annals of Family Medicine, Inc.
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September/October 2016
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Discordance Between Drug Adherence as Reported by Patients and Drug Importance as Assessed by Physicians
Stéphanie Sidorkiewicz, Viet-Thi Tran, Cécile Cousyn, Elodie Perrodeau, Philippe Ravaud
The Annals of Family Medicine Sep 2016, 14 (5) 415-421; DOI: 10.1370/afm.1965

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Discordance Between Drug Adherence as Reported by Patients and Drug Importance as Assessed by Physicians
Stéphanie Sidorkiewicz, Viet-Thi Tran, Cécile Cousyn, Elodie Perrodeau, Philippe Ravaud
The Annals of Family Medicine Sep 2016, 14 (5) 415-421; DOI: 10.1370/afm.1965
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