RT Journal Article SR Electronic T1 A High Sense of Coherence as Protection Against Adverse Health Outcomes in Patients Aged 80 Years and Older JF The Annals of Family Medicine JO Ann Fam Med FD American Academy of Family Physicians SP 337 OP 343 DO 10.1370/afm.1950 VO 14 IS 4 A1 Pauline Boeckxstaens A1 Bert Vaes A1 An De Sutter A1 Isabelle Aujoulat A1 Gijs van Pottelbergh A1 Catharina Matheï A1 Jean-Marie Degryse YR 2016 UL http://www.annfammed.org/content/14/4/337.abstract AB PURPOSE We set out to assess whether a high sense of coherence (SOC) protects from adverse health outcomes in patients aged 80 years and older who have multiple chronic diseases.METHODS A population-based prospective cohort study in 29 primary care practices throughout Belgium included 567 individuals aged 80 years and older. We plotted the highest tertile of SOC scores in Kaplan-Meier curves representing 3-year mortality and time to first hospitalization. Using Cox proportional hazard regression analyses and multiple logistic regression analyses adjusted for sociodemographic characteristics, depression, cognition, disability, and multimorbidity we examined the relationship between SOC and mortality, hospitalization, and decline in performance of activities of daily living (ADL).RESULTS Subjects with high SOC scores showed a higher cumulative survival than others (Log rank = 0.004) independent of other prognostic characteristics (adjusted hazard ratio 0.62 (95% CI, 0.38–1.00), P = .049). For ADL decline, a high SOC was shown to be protective, and this effect tended to be independent from the covariates under study (adjusted odds ratio 0.56 (95% CI, 0.31–1.0), P = .05).CONCLUSION Even very elderly persons with high SOC scores were shown to have lower mortality rates and less functional decline. These effects were independent of multimorbidity, depression, cognition, disability, and sociodemographic characteristics.