PT - JOURNAL ARTICLE AU - Fortin, Martin AU - Stewart, Moira AU - Ngangue, Patrice AU - Almirall, José AU - Bélanger, Mathieu AU - Brown, Judith Belle AU - Couture, Martine AU - Gallagher, Frances AU - Katz, Alan AU - Loignon, Christine AU - Ryan, Bridget L. AU - Sampalli, Tara AU - Wong, Sabrina T. AU - Zwarenstein, Merrick TI - Scaling Up Patient-Centered Interdisciplinary Care for Multimorbidity: A Pragmatic Mixed-Methods Randomized Controlled Trial AID - 10.1370/afm.2650 DP - 2021 Mar 01 TA - The Annals of Family Medicine PG - 126--134 VI - 19 IP - 2 4099 - http://www.annfammed.org/content/19/2/126.short 4100 - http://www.annfammed.org/content/19/2/126.full SO - Ann Fam Med2021 Mar 01; 19 AB - PURPOSE To measure the effectiveness of a 4-month interdisciplinary multifaceted intervention based on a change in care delivery for patients with multimorbidity in primary care practices.METHODS A pragmatic randomized controlled trial with a mixed-methods design in patients aged 18 to 80 years with 3 or more chronic conditions from 7 family medicine groups (FMGs) in Quebec, Canada. Health care professionals (nurses, nutritionists, kinesiologists) from the FMGs were trained to deliver the patient-centered intervention based on a motivational approach and self-management support. Primary outcomes: self-management (Health Education Impact Questionnaire); and self-efficacy. Secondary outcomes: health status, quality of life, and health behaviors. Quantitative analyses used multi-level mixed effects and generalized linear mixed models controlling for clustering within FMGs. We also conducted in-depth interviews with patients, family members, and health care professionals.RESULTS The trial randomized 284 patients (144 in intervention group, 140 in control group). The groups were comparable. After 4 months, the intervention showed a neutral effect for the primary outcomes. There was significant improvement in 2 health behaviors (healthy eating with odds ratios [OR] 4.36; P = .006, and physical activity with OR 3.43; P = .023). The descriptive qualitative evaluation revealed that the patients reinforced their self-efficacy and improved their self-management which was divergent from the quantitative results.CONCLUSIONS Quantitatively, this intervention showed a neutral effect on the primary outcomes and substantial improvement in 2 health behaviors as secondary outcomes. Qualitatively, the intervention was evaluated as positive. The combination of qualitative and quantitative designs proved to be a good design for evaluating this complex intervention.