RT Journal Article SR Electronic T1 Integrating behavioral health & primary care for multiple chronic diseases: Clinical trial of a practice redesign toolkit JF The Annals of Family Medicine JO Ann Fam Med FD American Academy of Family Physicians SP 2679 DO 10.1370/afm.20.s1.2679 VO 20 IS Supplement 1 A1 Littenberg, Benjamin A1 Reynolds, Paula A1 Natkin, Lisa A1 van Eeghen, Constance A1 Callas, Peter A1 Pace, Wilson A1 Rose, Gail A1 Hitt, Juvena A1 Crocker, Abigail A1 Mullin, Daniel A1 Baldwin, Laura-Mae A1 Bonnell, Levi A1 Waddell, Elizabeth A1 Pinckney, Richard A1 Frisbie, Sylvie A1 Mollis, Brenda A1 Macchi, C.R. A1 Nagykaldi, Zsolt A1 Teng, Kathryn A1 Stange, Kurt A1 O’Rourke-Lavoie, Jennifer A1 Stephens, Kari A1 Sieber, William A1 Jewiss, Jennifer A1 Scholle, Sarah A1 Pearson, Lauren Eidt A1 Leibowitz, George A1 Breshears, Ryan A1 Clifton, Jessica A1 Kathol, Roger A1 Stancin, Terry A1 McGovern, Mark A1 Hekman, Mary A1 Pomeroy, Douglas YR 2022 UL http://www.annfammed.org/content/20/Supplement_1/2679.abstract AB Context: Most patients in need of behavioral health (BH) care are seen in primary care, which often has difficulty responding. Some practices integrate behavioral health care (IBH), with medical and BH providers at the same location, working as a team. However, it is difficult to achieve high levels of integration.Objective: Test the effectiveness of a practice intervention designed to increase BH integration.Study Design: Pragmatic, cluster-randomized controlled trial.Setting: 43 primary care practices with on-site BH services in 13 states.Population: 2,460 adults with multiple chronic medical and behavioral conditions.Intervention: 24-month practice change process including an online curriculum, a practice redesign and implementation workbook, remote quality improvement coaching services, and an online learning community.Outcomes: Primary outcomes were changes in the 8 Patient-Reported Outcomes Measurement Information System (PROMIS-29) domain scores. Secondary outcomes were changes in medication adherence, self-reported healthcare utilization, time lost due to disability, cardiovascular capacity, patient centeredness, provider empathy, and several condition-specific measures. A sample of practice staff completed the Practice Integration Profile at each time point to estimate the degree of BH integration in that site. Practice-level case studies estimated the typical costs of implementing the intervention.Results: The intervention had no significant effect on any of the primary or secondary outcomes. Subgroup analyses showed no convincing patterns of effect in any populations. COVID-19 was apparently not a moderating influence of the effect of the intervention on outcomes. The intervention had a modest effect on the degree of practice integration, reaching statistical significance in the Workflow domain. The median cost of the intervention was $18,204 per practice. In post-hoc analysis, level of BH integration was associated with improved patient outcomes independent of the intervention, both at baseline and longitudinally.Conclusions: The specific intervention tested in this study was inexpensive, but had only a small impact on the degree of BH integration, and none on patient outcomes. However, practices that had more integration at baseline had better patient outcomes, independent of the intervention. Although this particular intervention was ineffective, IBH remains an attractive strategy for improving patient outcomes.