RT Journal Article SR Electronic T1 Home-Based Activity Program for Older People With Depressive Symptoms: DeLLITE–A Randomized Controlled Trial JF The Annals of Family Medicine JO Ann Fam Med FD American Academy of Family Physicians SP 214 OP 223 DO 10.1370/afm.1093 VO 8 IS 3 A1 Kerse, Ngaire A1 Hayman, Karen J. A1 Moyes, Simon A. A1 Peri, Kathy A1 Robinson, Elizabeth A1 Dowell, Anthony A1 Kolt, Gregory S. A1 Elley, C. Raina A1 Hatcher, Simon A1 Kiata, Liz A1 Wiles, Janine A1 Keeling, Sally A1 Parsons, John A1 Arroll, Bruce YR 2010 UL http://www.annfammed.org/content/8/3/214.abstract AB PURPOSE We wanted to assess the effectiveness of a home-based physical activity program, the Depression in Late Life Intervention Trial of Exercise (DeLLITE), in improving function, quality of life, and mood in older people with depressive symptoms. METHODS We undertook a randomized controlled trial involving 193 people aged 75 years and older with depressive symptoms at enrollment who were recruited from primary health care practices in Auckland, New Zealand. Participants received either an individualized physical activity program or social visits to control for the contact time of the activity intervention delivered over 6 months. Primary outcome measures were function, a short physical performance battery comprising balance and mobility, and the Nottingham Extended Activities of Daily Living scale. Secondary outcome measures were quality of life, the Medical Outcomes Study 36-item short form, mood, Geriatric Depression Scale (GDS-15), physical activity, Auckland Heart Study Physical Activity Questionnaire, and self-report of falls. Repeated measures analyses tested the differential impact on outcomes over 12 months’ follow-up. RESULTS The mean age of the participants was 81 years, and 59% were women. All participants scored in the at–risk category on the depression screen, 53% had a Diagnostic and Statistical Manual of Mental Disorders or International Classification of Diseases, Tenth Revision diagnosis of major depression or scored more than 4 on the GDS-15 at baseline, indicating moderate or severe depression. Almost all participants, 187 (97%), completed the trial. Overall there were no differences in the impact of the 2 interventions on outcomes. Mood and mental health related quality of life improved for both groups. CONCLUSION The DeLLITE activity program improved mood and quality of life for older people with depressive symptoms as much as the effect of social visits. Future social and activity interventions should be tested against a true usual care control.