RT Journal Article
SR Electronic
T1 Making Personalized Health Care Even More Personalized: Insights From Activities of the IOM Genomics Roundtable
JF The Annals of Family Medicine
JO Ann Fam Med
FD American Academy of Family Physicians
SP 373
OP 380
DO 10.1370/afm.1772
VO 13
IS 4
A1 Sean P. David
A1 Samuel G. Johnson
A1 Adam C. Berger
A1 W. Gregory Feero
A1 Sharon F. Terry
A1 Larry A. Green
A1 Robert L. Phillips, Jr
A1 Geoffrey S. Ginsburg
YR 2015
UL http://www.annfammed.org/content/13/4/373.abstract
AB Genomic research has generated much new knowledge into mechanisms of human disease, with the potential to catalyze novel drug discovery and development, prenatal and neonatal screening, clinical pharmacogenomics, more sensitive risk prediction, and enhanced diagnostics. Genomic medicine, however, has been limited by critical evidence gaps, especially those related to clinical utility and applicability to diverse populations. Genomic medicine may have the greatest impact on health care if it is integrated into primary care, where most health care is received and where evidence supports the value of personalized medicine grounded in continuous healing relationships. Redesigned primary care is the most relevant setting for clinically useful genomic medicine research. Taking insights gained from the activities of the Institute of Medicine (IOM) Roundtable on Translating Genomic-Based Research for Health, we apply lessons learned from the patient-centered medical home national experience to implement genomic medicine in a patient-centered, learning health care system.