RT Journal Article SR Electronic T1 Changes in the Ambulatory Use of Antibiotics in France Due to the COVID-19 Pandemic in 2020-2022: A Nationwide Time-Series Analysis JF The Annals of Family Medicine JO Ann Fam Med FD American Academy of Family Physicians SP 158 OP 161 DO 10.1370/afm.230633 VO 23 IS 2 A1 Rousselot, Nicolas A1 Brayan, Tchassim A1 Dumartin, Catherine A1 Clément, Mathieu A1 Pariente, Antoine YR 2025 UL http://www.annfammed.org/content/23/2/158.abstract AB We estimated the changes in the ambulatory use of antibiotics in France due to the COVID-19 pandemic in 2020-2022 by conducting time-series analyses using nationwide data from French health insurance databases. We examined all systemic antibiotics dispensed from January 1, 2010 through March 31, 2022. Use of most antibiotics decreased during the 3-month period following the start of first lockdown (March 17, 2020), and these decreases persisted 12 months later. Some initial increases indicated potential stockpiling for antibiotics used for chronic indications. Azithromycin constituted a noticeable exception. In a context of reduced circulation of non–COVID-19 viruses, the observed decreases compared with forecasts could partly reflect habitual overuse of certain antibiotics.