Table 1

Definition and Data Source for Probabilities

TermExplanationData Source
P(RTI)Probability of a person consulting with RTI in a 30-day periodFrom RTI consultation rate per 30 days in CPRD
P(AB|RTI)Probability of receiving an AB prescription on the same date as an RTI consultationFrom proportion of RTI consultations with AB prescribed, from CPRD
P(PTA)Probability of PTA, per 30 daysFrom incidence of PTA in CPRD
P(RTI|PTA)Probability of patients with PTA having consulted for an RTI in the 30 days preceding their PTA diagnosisProportion of PTA cases with previous RTI consultation, calculated from CPRD
P(PTA|RTI)Probability of PTA arising in the 30 days following an RTI consultation Embedded Image
 P(PTA|[AB|RTI])Probability of patients with PTA having consulted for an RTI and received AB prescription Embedded Image
 P(PTA|[No AB|RTI])Probability of patients with PTA having consulted for an RTI and not received an AB prescription Embedded Image
NNTThe number of additional antibiotic prescriptions required to prevent 1 case of PTA Embedded Image
  • AB = antibiotic; CPRD = Clinical Practice Research Datalink; NNT = number needed to treat; P = probability; PTA = peritonsillar abscess; RTI = respiratory tract infection.