Adjusted Difference in Outcomes for Trust-Enhanced e-Consent Compared With the Standard and Interactive e-Consents at 6-Month Follow-Up
| Outcomes | Interactive vs Standard, B (SE) | P Value | Trust-Enhanced vs Standard, B (SE) | P Value | Trust-Enhanced vs Interactive, B (SE) | P Value |
|---|---|---|---|---|---|---|
| Satisfaction with decision | 0.43 (0.09) | P <.001 | 0.87 (0.09) | P <.001 | 0.43 (0.07) | P <.001 |
| Subjective understanding | 18.04 (2.58) | P <.001 | 32.19 (2.64) | P <.001 | 14.09 (2.42) | P <.001 |
| Objective knowledge | 1.21 (0.18) | P <.001 | 2.12 (0.18) | P <.001 | 0.92 (0.16) | P <.001 |
| Perceived voluntariness | 0.81 (0.66) | P = .22 | 3.97 (0.64) | P <.001 | 3.18 (0.68) | P <.001 |
| Trust in medical researchers | 6.63 (0.91) | P <.001 | 12.50 (0.95) | P <.001 | 5.90 (0.90) | P <.001 |
B = regression coefficient; e-consent = electronic consent; SE = standard error.
Notes: Multivariate results represent data from 732 unique participants with 1 to 3 observations per participant due to attrition. Two participants were excluded because of missing data for age. All models include controls for participant age, sex, race, ethnicity, education, version, and time point (full model estimates available in supplemental materials, https://www.AnnFamMed.org/content/19/1/16/suppl/DC1/). Effect estimates and associated SE represent the interaction of e-consent version (standard, interactive, and trust-enhanced) with time point (6 months).