Response, Remission, SMD, and Acceptability for Psychotherapy, Pharmacotherapy, and Combined Treatment Compared With Each Other and Control Conditions (CAU, Waitlist, Placebo)3
| Acceptability | ||||||
|---|---|---|---|---|---|---|
| Response | Combined | 1.11 (0.65-1.90) | 1.00 (0.57-1.76) | 0.81 (0.42-1.58) | 0.93 (0.52-1.67) | 0.84 (0.41-1.72) |
| 1.30 (0.98-1.73) | Pharmacotherapy | 0.90 (0.69-1.18) | 0.73 (0.48-1.11) | 0.84 (0.61-1.15) | 0.75 (0.44-1.28) | |
| 1.35 (1.00-1.81) | 1.03 (0.88-1.22) | Psychotherapy | 0.81 (0.53-1.25) | 0.93 (0.78-1.10) | 0.83 (0.53-1.31) | |
| 1.65 (1.10-2.46) | 1.26 (0.94-1.71) | 1.22 (0.90-1.66) | Pill placebo | 1.15 (0.72-1.82) | 1.03 (0.55-1.93) | |
| 2.15 (1.56-2.97) | 1.65 (1.35-2.03) | 1.60 (1.40-1.83) | 1.31 (0.94-1.81) | CAU | 0.90 (0.55-1.45) | |
| 3.16 (1.91-5.21) | 2.43 (1.57-3.74) | 2.35 (1.57-3.51) | 1.92 (1.16-3.17) | 1.47 (0.96-2.23) | Waitlist | |
| Standardized Mean Difference | ||||||
|---|---|---|---|---|---|---|
| Remission | Combined | 0.29 (–0.03 to 0.60) | 0.26 (–0.07 to 0.59) | 0.54 (0.06-1.02) | 0.70 (0.35-1.05) | 1.13 (0.64-1.61) |
| 1.25 (0.77-2.04) | Pharmacotherapy | –0.03 (–0.22 to 0.17) | 0.25 (–0.13 to 0.63) | 0.41 (0.18-0.64) | 0.84 (0.44-1.24) | |
| 1.35 (0.81-2.26) | 1.08 (0.87-1.34) | Psychotherapy | 0.28 (–0.10 to 0.66) | 0.44 (0.31-0.57) | 0.86 (0.51-1.22) | |
| 1.74 (0.95-3.20) | 1.39 (0.95-2.03) | 1.29 (0.88-1.88) | Placebo | 0.16 (–0.24 to 0.56) | 0.59 (0.07-1.10) | |
| 2.09 (1.22-3.58) | 1.67 (1.28-2.18) | 1.55 (1.29-1.85) | 1.20 (0.79 to 1.82) | CAU | 0.43 (0.05-0.80) | |
| 3.26 (1.57-6.77) | 2.60 (1.48-4.58) | 2.41 (1.43-4.06) | 1.87 (0.98 to 3.56) | 1.56 (0.90-2.70) | Waitlist | |
CAU = care as usual; RR = relative risk; SMD = standardized mean difference.
Note: Data are shown as RR (95% CI) (upper panel and lower left of lower panel) or SMD (95% CI) (upper right of lower panel).
a In the lower left triangle of the upper part of the table, RR >1 means that the column-defining intervention increases the event of interest compared with the row-defining intervention. Therefore, the former is more efficacious than the latter. In the upper right triangle, RR >1 means that the row-defining intervention increases the event of interest compared with the column-defining intervention. Therefore, the former is less acceptable than the latter. In the lower left triangle of the lower portion of the table, RR >1 means that the column-defining intervention increases the event of interest compared with the row-defining intervention. In the upper right triangle, SMD >0 means that the row-defining intervention is more effective compared to the column-defining intervention.