Table 4.

Incidence Rate Ratios for Achilles Tendon Rupture by Antibiotic Type

Antibiotic TypeIncidence Rate Ratio (95% CI)
First- and second-generation fluoroquinolones2.94 (1.90-4.54)
Third-generation fluoroquinolones1.05 (0.33-3.37)
Nonfluoroquinolones1.08 (0.80-1.47)
  • Note: For each patient, comparator was the period with no antibiotic exposure.