Baseline Characteristics of Patients in the Study Groups
| Characteristic | Physical Activity n = 158 | Antidepressant Treatment n = 155 | P Value |
|---|---|---|---|
| Sociodemographic characteristics, No. (%) | |||
| Age, y | .55 | ||
| 65-74 | 102 (64.6) | 95 (61.3) | |
| ≥75 | 56 (35.4) | 60 (38.7) | |
| Sex | .437 | ||
| Female | 127 (80.4) | 119 (76.8) | |
| Male | 31 (19.6) | 36 (23.2) | |
| Educational level | .535 | ||
| Illiterate or primary education | 124 (78.5) | 126 (81.3) | |
| Secondary or university education | 34 (21.5) | 29 (18.7) | |
| Social class | .401 | ||
| I-IIIa | 23 (14.6) | 28 (18.1) | |
| IV-Vb | 135 (85.4) | 127 (81.9) | |
| Marital status | .895 | ||
| Single, widowed, or divorced | 59 (37.3) | 59 (38.1) | |
| Married | 99 (62.7) | 96 (61.9) | |
| Lifestyle, No. (%) | |||
| Smoker | .55 | ||
| Yes | 16 (10.1) | 19 (12.3) | |
| No | 142 (89.9) | 136 (87.7) | |
| Alcohol consumption | .61 | ||
| > 100 g/week | 8 (5.1) | 6 (3.9) | |
| <100 g/week | 150 (94.9) | 149 (96.1) | |
| Physical activity | .412 | ||
| Physical inactivity | 30 (19.0) | 24 (15.5) | |
| Moderate or intense activity | 128 (81.0) | 131 (84.5) | |
| Health status, No. (%) | .707 | ||
| Multimorbidity (≥3 diseases) | .343 | ||
| Yes | 145 (91.8) | 144 (92.9) | |
| No | 13 (8.2) | 11 (7.1) | |
| Polypharmacy (≥4 drugs) | .501 | ||
| Yes | 115 (72.8) | 120 (77.4) | |
| No | 43 (27.2) | 35 (22.6) | |
| History of depressive disorder(s) | .704 | ||
| Yes | 93 (58.9) | 97 (62.6) | |
| No | 65 (41.1) | 58 (37.4) | |
| Prior use of antidepressant drug(s) | .342 | ||
| Yes | 69 (43.7) | 71 (45.8) | |
| No | 89 (56.3) | 84 (54.2) | |
| Obesity | .465 | ||
| Yes | 69 (43.7) | 76 (49.0) | |
| No | 89 (56.3) | 79 (51.0) | |
| Arterial hypertension | .921 | ||
| Yes | 84 (53.2) | 76 (49.0) | |
| No | 74 (46.8) | 79 (51.0) | |
| Self-perception of health (Euro-Qol-5D questionnaire), No. (%) | |||
| Mobility problems | .921 | ||
| Yes | 40 (25.3) | 40 (25.8) | |
| No | 118 (74.7) | 115 (74.2) | |
| Self-care problems | .985 | ||
| Yes | 2 (1.3) | 2 (1.3) | |
| No | 156 (98.7) | 153 (98.7) | |
| Problems performing daily activities | .915 | ||
| Yes | 20 (12.7) | 19 (12.3) | |
| No | 138 (87.3) | 136 (87.7) | |
| Pain or discomfort | .89 | ||
| Yes | 111 (70.3) | 110 (71.0) | |
| No | 47 (29.7) | 45 (29.0) | |
| Anxiety or depression | .255 | ||
| Yes | 128 (81.0) | 133 (85.8) | |
| No | 30 (19.0) | 22 (14.2) | |
| Health status score, mean (SD) | 59.2 (18.6) | 57.1 (16.4) | .287 |
| MADRS score, mean (SD) | 15.1 (4.6) | 15.9 (3.9) | .106 |