Table 1.

Characteristics of Children Aged 3 to 17 Years With Asthma in the ADVANCE Clinical Research Network, 2012-2018

Racial, Ethnic, and Language Group
CharacteristicAll (N = 41,276)Non-Hispanic White (n = 10,164)Non-Hispanic Black (n = 10,041)Latine, Prefer English (n = 9,239)Latine, Prefer Spanish (n = 11,832)
Female, No. (%)17,709 (42.9)4,429 (43.6)4,257 (42.4)4,011 (43.4)5,012 (42.4)
Age at first visit, mean (SD), y         7.6 (3.7)         8.2 (3.8)         7.6 (3.7)         7.6 (3.7)         6.9 (3.4)
BMI category, No. (%)a
    Never overweight16,726 (40.5)4,663 (45.9)4,565 (45.5)3,592 (38.9)3,906 (33.0)
    Sometimes overweight10,083 (24.4)2,222 (21.9)2,233 (22.2)2,261 (24.5)3,367 (28.5)
    Always overweight14,467 (35.0)3,279 (32.3)3,243 (32.3)3,386 (36.6)4,559 (38.5)
Payor type, No. (%)
    Never insured1,122 (2.7)275 (2.7)188 (1.9)264 (2.9)395 (3.3)
    Some private2,423 (5.9)1,140 (11.2)409 (4.1)618 (6.7)256 (2.2)
    Some private and public3,324 (8.1)984 (9.7)659 (6.6)1,003 (10.9)678 (5.7)
Some public34,407 (83.4)7,765 (76.4)8,785 (87.5)7,354 (79.6)10,503 (88.8)
Federal poverty level, No. (%)
    Always >138%2,916 (7.1)1,029 (10.1)805 (8.0)620 (6.7)462 (3.9)
    Above and below 138%5,151 (12.5)1,350 (13.3)946 (9.4)930 (10.1)1,925 (16.3)
    Always ≤138%28,103 (68.1)5,973 (58.8)7,072 (70.4)6,437 (69.7)8,621 (72.9)
    Not documented5,106 (12.4)1,812 (17.8)1,218 (12.1)1,252 (13.6)824 (7.0)
Urbanicity, No. (%)b
    Metropolitan35,401 (85.8)7,507 (73.9)9,619 (95.8)7,174 (77.6)11,101 (93.8)
    Micropolitan4,493 (10.9)1,998 (19.7)183 (1.8)1,705 (18.5)607 (5.1)
    Rural1,382 (3.3)659 (6.5)239 (2.4)360 (3.9)124 (1.0)
US region, No. (%)
    Northeast4,129 (10.0)228 (2.2)1,449 (14.4)1,163 (12.6)1,289 (10.9)
    South17,515 (42.4)3,819 (37.6)5,293 (52.7)3,677 (39.8)4,726 (39.9)
    Midwest3,819 (9.3)708 (7.0)2,457 (24.5)356 (3.9)298 (2.5)
    West15,813 (38.3)5,409 (53.2)842 (8.4)4,043 (43.8)5,519 (46.6)
Visits per year, No. (%)
    ≤117,900 (43.4)5,005 (49.2)5,420 (54.0)3,914 (42.4)3,561 (30.1)
    2 or 38,015 (19.4)1,825 (18.0)1,933 (19.3)1,790 (19.4)2,467 (20.9)
    ≥415,361 (37.2)3,334 (32.8)2,688 (26.8)3,535 (38.3)5,804 (49.1)
Maximum asthma severity, No. (%)c
    Intermittent11,348 (27.5)2,537 (25.0)3,324 (33.1)2,169 (23.5)3,318 (28.0)
    Mild persistent6,541 (15.8)1,193 (11.7)1,780 (17.7)1,691 (18.3)1,877 (15.9)
    Moderate to severe persistent3,583 (8.7)787 (7.7)1,062 (10.6)757 (8.2)977 (8.3)
    Not documented19,804 (48.0)5,647 (55.6)3,875 (38.6)4,622 (50.0)5,660 (47.8)
Influenza vaccination rate, No. (%)
    <50% annually28,851 (69.9)8,019 (78.9)7,332 (73.0)6,743 (73.0)6,757 (57.1)
    50% to 80% annually8,685 (21.0)1,542 (15.2)1,968 (19.6)1,771 (19.2)3,404 (28.8)
    ≥80% annually3,740 (9.1)603 (5.9)741 (7.4)725 (7.8)1,671 (14.1)
Pneumococcal vaccination ever, No. (%)26,560 (64.3)5,585 (54.9)6,705 (66.8)5,677 (61.4)8,593 (72.6)
Smoker, No. (%)
    Never26,905 (65.2)6,136 (60.4)6,048 (60.2)6,010 (65.1)8,711 (73.6)
    Ever969 (2.3)424 (4.2)262 (2.6)163 (1.8)120 (1.0)
    Passive only3,018 (7.3)1,566 (15.4)665 (6.6)408 (4.4)379 (3.2)
    Not documented10,384 (25.2)2,038 (20.1)3,066 (30.5)2,658 (28.8)2,622 (22.2)
Albuterol prescriptions per year, mean (SD)         0.6 (0.6)         0.5 (0.6)         0.7 (0.7)         0.6 (0.6)         0.7 (0.7)
Inhaled corticosteroid prescription ever, No. (%)12,267 (29.7)2,860 (28.1)2,944 (29.3)2,411 (26.1)4,052 (34.2)
  • ADVANCE = Accelerating Data Value Across a National Community Health Center; BMI = body mass index; RUCA = rural-urban commuting area; US = United States.

  • Notes: All children had at least 1 year of observation. Data are representative of 345 clinics spanning 18 US states and 4 regions: Northeast (Massachusetts, Rhode Island), South (Florida, Georgia, Maryland, North Carolina), Midwest (Indiana, Kansas, Missouri, Ohio, Wisconsin), and West (Alaska, California, Hawaii, Nevada, New Mexico, Oregon, Washington).

  • a Overweight if BMI >85th percentile. Category reflects all available measures during study period. Biologically implausible values were flagged as more than 8 SDs above or 4 SDs below mean BMI.

  • b RUCA classification code based on 2010 census tract information and patients’ primary clinic zip code.

  • c Maximum asthma severity diagnosed in an ambulatory visit encounter or documented in the patient problem list.