Table 5.

Disease Management Therapy of COPD Patients in COPD-RD and APEX-COPD Registry

Type of TherapyInhaled TherapyCOPD-RD (n = 17,192), No. (%)APEX-COPD Registry (n = 1,354), No. (%)P Value
NoneNo therapy    565 (3.3)103 (7.6) 
Reliever onlySABA, SAMA, SABA+SAMA1,587 (9.2)  66 (4.9) 
Controller therapyLABAa     46 (0.3)    4 (0.3) 
LAMAa2,127 (12.4)  55 (4.1) 
LABA + LAMAa2,265 (13.2)240 (17.7).000
ICSa   756 (4.4)  47 (3.5) 
ICS + LABAa5,070 (29.5)325 (24.0) 
ICS + LAMAa      66 (0.4)    5 (0.4) 
ICS + LABA + LAMAa4,658 (27.1)509 (37.6) 
Macrolidesb8,087 (47.0)613 (45.3) 
  • APEX = Advancing the Patient Experience; COPD = chronic obstructive pulmonary disease; COPD-RD = COPD Optimum Patient Care DARTNet Research Database; ICS = inhaled corticosteroids; LABA = long-acting β2-agoninst; LAMA = long-acting muscarinic antagonist; SABA = short-acting β-agonist; SAMA = short-acting muscarinic antagonist.

  • a May be prescripted with or without reliever therapy.

  • b Any macrolide code in last 12 months.