Table 4.

Iteration 4: Refining Rationale and Organization in the Joint Display

Joint Display of Integrated Mixed Methods Data Collection
Construct	Patient-Caregiver Mixed Methods Survey^{^a}		Clinical Variables From Medical Record Abstraction		Rationale of Organization (Example Questions)
Construct	Quantitative Questions	Qualitative Questions	Quantitative Clinical Variables	Qualitative Clinical Variables	Rationale of Organization (Example Questions)
Role Functioning	1. I can keep up with household tasks 13. How would you describe your child’s level of dependence?	9. What is it like caring for your child when they have fever neutropenia? 2. What are the extra resources and help required to keep your family functioning during fever neutropenia episodes?	Admission characteristics: Hospital LOS Readmission Episode characteristics Was a cause of FN identified? If so, what? Demographics: Age, gender, ethnicity	Risk stratification: High risk or low risk Type of outpatient follow-up (virtual vs in-person)	Integration of data from clinical course and outcomes that may or may not impact caregiver role functioning within nuclear family (eg, Do caregivers with shorter LOS report improved role functioning?)
Emotional Functioning	6. What is your overall level of concern for your child’s health and condition during this fever neutropenia episode? 8. During this fever neutropenia episode, I am confident in my ability to care for my child. 10. I am satisfied with the overall care my child received. 12. How would you describe your child’s mood?	7. How has your child’s illness emotionally affected you?	Oncologic history: Primary diagnosis Date of diagnosis Phase of therapy Disease status Admission characteristics: Hospital LOS Readmission Episode characteristics Was a cause of FN identified? If so, what? Demographics: Age, gender, ethnicity Episode characteristics Was a cause of FN identified? If so, what?	Discharger/follow-up description: Type of follow-up (telephone, video, clinic) Who did follow-up visits (RN, NP, fellow, attending)? Frequency of follow-up visits RN, parent, provider concerns documented Risk stratification: High risk or low risk Admission characteristics: Hospital LOS Readmission PICU admission characteristics, LOS	Integration of data from clinical course and outcomes that may or may not impact caregiver and patient emotional functioning (eg, Do caregivers with a certain type of follow-up visit feel more confident in providing care?)
Cognitive Functioning	16. How would you describe your child’s interest or concentration? 18. How would you describe your child’s quality of sleep? 19. How would you describe your child’s activity or energy level?	17. How have school and work been affected by your child’s illness?	PICU admission: LOS ≤3 days Acute respiratory failure present Need for advanced airway NIPPV or HFNC? Need for pressor support	PICU admission: Related to FN Noninfectious concern Disease status Evidence of shock Risk stratification: High risk or low risk	Integration of data from clinical course and outcomes that may or may not impact patient/caregiver perception of patient’s subjective measures of cognitive function (eg, Is activity level affected by persistent N/V, typhlitis, need for IV narcotics, longer length antibiotics, LOS?)
Social Functioning	3. I am able to spend time with my partner 4. I am able to spend time with my other children and/or family	5. How did this fever neutropenia episode affect members in your family?	Admission characteristics: Hospital LOS Readmission Episode characteristics Was a cause of FN identified? If so, what?	Type of outpatient follow-up (virtual vs in-person)	Integration of data from clinical course and outcomes that may or may not impact caregiver social functioning (eg, Were repeat trips back to the hospital or clinic more difficult for siblings?)
Symptom Severity	14. How would you describe your child’s appetite?	15. How are symptoms different when your child is at home versus in the hospital?	Persistent nausea, vomiting or C diff present? Admission characteristics: Hospital LOS Readmission Episode characteristics Was a cause of FN identified? If so, what?	Evidence of mucositis or typhlitis? Severe pain with IV narcotic requirement	Integration of data from clinical course and outcomes that may or may not impact subjective measures of symptom severity (eg, Do caregivers notice gastrointestinal problems impact their child’s appetite?)
Global Functioning	11. What is your child’s overall happiness and well-being?	20. In your opinion, what is the most important value when your child has fever neutropenia? 21. Is there anything else you would like to share about caring for your child during fever neutropenia?	Admission characteristics: Hospital LOS Readmission PICU admission, LOS Oncologic history: Primary diagnosis Disease status	Risk stratification: High risk or low risk Admission characteristics: Hospital LOS Readmission PICU LOS	Integration of data from clinical course and outcomes that may or may not impact the global perspective of care delivery (eg, Does a high-risk episode or a severe outcome impact a care-giver’s report of patient well-being?)

C diff = Clostridioides difficile; FN = febrile neutropenia; HFNC = high-flow nasal cannula; IV = intravenous; LOS = length of stay; NIPPV = noninvasive positive pressure ventilation; NP = nurse practitioner; N/V = nausea/vomiting; PICU = pediatric intensive care unit; RN = registered nurse.
↵a Italics denote patient (vs caregiver) was focus of the question.
Note: Table footnotes have been added to improve clarity and readability. They were notably absent in the original tables.