Table 4

Assessment of Attrition Bias: Completing Practices and All Practices With Imputation

MeasureUsual CareCRP TrainingCommunication TrainingCombination
Practices completing 12 months of follow-up
Patients prescribed antibiotics, %51.042.939.847.1
Difference, % (95% CI) [P value]aref−7 (−15 to 2) [.11]−7 (−15 to 1) [.09]−4 (−12 to 4) [.30]
All practices, with imputation for missing data
Patients prescribed antibiotics, %49.742.941.947.0
Difference, % (95% CI) [P value]aref−6 (−14 to 3) [.22]−7 (−15 to 1) [.10]−4 (−12 to 4) [.34]
  • CRP = C–reactive protein; ref = reference group.

  • Note: A practice-level analysis.

  • a Reduction in proportion compared with usual care controlling for baseline prescribing and practice-level averages of patient characteristics: age, type of infection (lower respiratory tract infection vs upper respiratory tract infection), presence of symptoms (crackles, wheeze, pulse higher than 100 beats per minute, temperature higher than 37.8°C), respiratory rate, physician’s rating of severity, and duration of cough.