Response to the Test Treatment With Prednisolone in 233 Patients With Persistent Cough
| Postbronchodilator | Total N=233 | COPD n=61 | Asthma n=25 | COPD and Asthma n=14 | No COPD or Asthma n=133 | P Value |
|---|---|---|---|---|---|---|
| Increased FEV1, median (SD), %a | 0 (9) | 1 (10) | 1 (4) | −5 (6) | 0 (9) | .01b |
| Increased FEV1, median (SD), mLc | 0 (190) | 20 (230) | 30 (130) | −100 (150) | 0 (170) | .01b |
| Responder: >12% or 200 mL, n (%) | 30 (13)d | 14 (23)e | 1 (4) | 1 (7) | 14 (11) | .03f |
COPD = chronic obstructive pulmonary disease; FEV1 = forced expiratory volume in 1 second.
↵a [(FEV1 posttest–FEV1 pretest)/FEV1 pretest]x100%.
↵b Kruskal Wallis test.
↵c FEV1 posttest–FEV1 pretest.
↵d In all 30 responders, FEV1 was >200 mL, and in 18 cases FEV1 was also >12% of baseline.
↵e Of these 14, 11 had mild and 3 had moderate to severe COPD.
↵f χ2 Test.