Postbronchodilator | Total N=233 | COPD n=61 | Asthma n=25 | COPD and Asthma n=14 | No COPD or Asthma n=133 | P Value |
---|---|---|---|---|---|---|
Increased FEV_{1}, median (SD), %^{a} | 0 (9) | 1 (10) | 1 (4) | −5 (6) | 0 (9) | .01^{b} |
Increased FEV_{1}, median (SD), mL^{c} | 0 (190) | 20 (230) | 30 (130) | −100 (150) | 0 (170) | .01^{b} |
Responder: >12% or 200 mL, n (%) | 30 (13)^{d} | 14 (23)^{e} | 1 (4) | 1 (7) | 14 (11) | .03^{f} |
COPD = chronic obstructive pulmonary disease; FEV_{1} = forced expiratory volume in 1 second.
↵a [(FEV_{1} posttest–FEV_{1} pretest)/FEV_{1} pretest]x100%.
↵b Kruskal Wallis test.
↵c FEV_{1} posttest–FEV_{1} pretest.
↵d In all 30 responders, FEV_{1} was >200 mL, and in 18 cases FEV_{1} was also >12% of baseline.
↵e Of these 14, 11 had mild and 3 had moderate to severe COPD.
↵f χ^{2} Test.