Intervention Clinic | Control Clinic | ||||||||
---|---|---|---|---|---|---|---|---|---|
Variable | No. | Baseline | Post-intervention | Change | Baseline | Post-intervention | Change | Intervention Effecta | P Valueb |
DBP = diastolic blood pressure; hemoglobin A1c=glycated hemoglobin; LDL=low-density lipoprotein; SBP=systolic blood pressure; SE=standard error. | |||||||||
a The intervention effect column illustrates the differential amount of change in the intervention arm relative to the control arm comparing before and after the intervention. | |||||||||
b For mean value analysis, P value associated with the time × condition term in a general linear mixed model with repeated time measurements, study arm, and their interaction. For proportion at goal analysis, P value associated with study arm. | |||||||||
c P <.001. | |||||||||
Hemoglobin A1c, mean (SE), % | 1,092 | 8.5 (0.09) | 7.9 (0.09) | −0.58c | 8.4 (0.08) | 8.1 (0.08) | −0.32c | −0.26 | .01 |
Hemoglobin A1c <7%, % (SE) | 1,144 | 78.4 (2.0) | 79.2 (2.0) | −0.8 | .80 | ||||
SBP, mean (SE), mm Hg | 894 | 141.3 (0.70) | 130.5 (0.70) | −10.8c | 141.6 (0.69) | 131.5 (0.69) | −10.1c | −0.70 | .56 |
SBP <130 mm Hg, % (SE) | 1,506 | 80.2 (1.6) | 75.1 (1.6) | 5.1 | .03 | ||||
DBP, mean (SE), mm Hg | 731 | 85.1 (0.52) | 76.8 (0.52) | −8.3c | 84.6 (0.51) | 77.1 (0.51) | −7.5c | −0.82 | .38 |
DBP <80 mm Hg, % (SE) | 1,669 | 85.6 (1.4) | 81.7 (1.5) | 3.9 | .07 | ||||
LDL cholesterol, mean (SE), mg/dL | 868 | 122.3 (1.7) | 97.9 (1.8) | −24.4c | 124.1 (1.7) | 98.3 (1.8) | −25.8c | 1.37 | .62 |
LDL cholesterol <100 mg/dL (or <70 mg/dL if heart disease), % (SE) | 1,362 | 85.2 (1.6) | 83.9 (1.5) | 1.4 | .53 |