Table 1

Performance Characteristics of the Self-Report ADE Measure (N = 859 Patients)

Estimated Value95% CI
Sensitivity29%27%-31%
Specificity93%92%-94%
PPV57%54%-60%
NPV81%80%-81%
LR+4.223.78-4.72
LR–0.760.74-0.78
  • ADE = adverse drug effect; LR+ = positive likelihood ratio; LR− = negative likelihood ratio; NPV = negative predictive value; PPV = positive predictive value.

  • Note: Based on the number of patients with an ADE (reported symptom established as an ADE, true and false positive and true and false negative).