Table 2

Adjusted Odds of MDD at 9 and/or 18 Months in the Overall Sample (N = 338)

CharacteristicGeneral Patient Characteristics
OR (95% CI)
Behavioral Variables
OR (95% CI)
Biologic Variables
OR (95% CI)
Psychosocial Variables
OR (95% CI)
Combined Model
OR (95% CI)
Age0.95a (0.92–0.99)0.96 (0.92–1.01)
Female1.64 (0.77–3.46)1.29 (0.50–3.30)
White race1.16 (0.55–2.45)0.96 (0.37–2.46)
Income0.99a (0.98–1.01)1.00 (0.98–1.01)
Diet adherence0.87 (0.70–1.08)
Exercise adherence0.95 (0.80–1.08)
Hemoglobin A1c1.22a(1.01–1.49)1.12 (0.87–1.43)
BMI1.04a (1.01–1.09)1.01 (0.95–1.08)
No. of comorbidities1.10 (0.97–1.25)
No. of diabetes complications0.87 (0.65–1.18)
Prior MDD4.15c (1.97–8.73)4.19b (1.79–9.79)
No. of negative life events1.11a (1.01–1.24)1.10 (0.98–1.24)
Negative affect at baseline1.08c (1.05–1.11)1.09c (1.05–1.13)
  • CI=confidence interval; BMI = body mass index; hemoglobin A1c=glycated hemoglobin; MDD=major depressive disorder; OR=odds ratio.

  • a P <.05.

  • b P=.001.

  • c P <.001.