Baseline Probability and Cost Assumptions for Influenza: Testing-Treatment Model
| Variable | Baseline Assumption | Sensitivity Test Range |
|---|---|---|
| * For benefits, a threshold analysis was performed (see Figure 3 and text). | ||
| Cost assumptions | ||
| Cost of diagnostic test, $ | 20.00 | 5–30 |
| Benefits of recovery, $ | 177.20 | * |
| Additional physician visit for drug reaction, $ | 40.48 | 32.38–48.54 |
| Complication with hospitalization, $ | 8,960.20 | 7,175–10,763 |
| Medication costs (full course of therapy) | ||
| Amantadine, $ | 10.50 | 8.40–12.60 |
| Rimantadine, $ | 24.08 | 19.26–28.90 |
| Zanamivir, $ | 49.35 | 39.48–59.22 |
| Oseltamivir, $ | 61.00 | 48.80–73.20 |
| Probability assumptions | ||
| Test sensitivity, % | 72.5 | 50–95 |
| Test specificity, % | 90.0 | 80–00 |
| Probability of drug side effect, % | 3.0 | 0–6 |
| Probability of influenza complication, % | 0.5 | 0.3–5 |