Percentage of Adult Survivors of Childhood Cancer Treated With Therapies Associated With Increased Risk for Late Effects Reporting an Absence of the Following Types of Outpatient Medical Care in a 2-Year Period, Compared With All Survivors
Absence of | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
General Medical Contact | General Physical Examination | Cancer-Related Medical Visit | Cancer Center Medical Visit | ||||||||||
Variable | Total No. | % | OR | (95% CI) | % | OR | (95% CI) | % | OR | (95% CI) | % | OR | (95% CI) |
Note: results adjusted for age, sex, and race; percentages are based upon the total with available data for each variable. | |||||||||||||
OR = odds ratio; CI = confidence intervals; RT = radiation therapy. | |||||||||||||
* High-risk therapy: treatment with any of the following: chest-mantle radiation, anthracycline >300 mg/m2, bleomycin, etoposide, or ifosfamide. | |||||||||||||
Chest-mantle RT | |||||||||||||
No | 6,013 | 12.5 | 1.00 | Referent | 30.6 | 1.00 | Referent | 59.4 | 1.00 | Referent | 79.7 | 1.00 | Referent |
Yes | 1,802 | 8.2 | 0.68 | 0.57–0.83 | 24.6 | 0.64 | 0.56–0.73 | 47.9 | 0.60 | 0.53–0.67 | 70.3 | 0.50 | 0.43–0.57 |
Anthracycline | |||||||||||||
<300 mg/m2 | 6,459 | 11.1 | 1.00 | Referent | 29.4 | 1.00 | Referent | 53.6 | 1.00 | Referent | 72.6 | 1.00 | Referent |
≥300 mg/m2 | 1,508 | 10.7 | 0.88 | 0.73–1.06z | 27.4 | 0.96 | 0.84–1.11 | 51.7 | 0.77 | 0.68–0.88 | 69.8 | 0.65 | 0.56–0.75 |
Bleomycin | |||||||||||||
No | 7,642 | 12.2 | 1.00 | Referent | 29.4 | 1.00 | Referent | 58.4 | 1.00 | Referent | 81.5 | 1.00 | Referent |
Yes | 581 | 7.8 | 0.58 | 0.42–0.81 | 25.7 | 0.80 | 0.65–0.99 | 40.8 | 0.48 | 0.40–0.58 | 67.0 | 0.47 | 0.38–0.57 |
High-risk therapy* | |||||||||||||
No | 4,304 | 13.2 | 1.00 | Referent | 31.3 | 1.00 | Referent | 61.9 | 1.00 | Referent | 83.1 | 1.00 | Referent |
Yes | 3,449 | 10.0 | 0.70 | 0.60–0.82 | 26.4 | 0.74 | 0.66–0.83 | 50.7 | 0.58 | 0.53–0.65 | 71.1 | 0.45 | 0.39–0.50 |