High-Cost Drug Categories
| Prescription Category | Baseline Mean $ (SE) | Study Period Mean $ (SE) | Change From Baseline | P * Value |
|---|---|---|---|---|
| Note: values are least squares mean (SE). P >.1 for all baseline comparisons except rhinitis medications (P = .03) and triptan and headache medications (P = .07). | ||||
| GERD = gastroesophageal reflux disease, COX-2 inhibitors = selective cyclooxygenase 2 inhibitors, NSAIDs = nonsteroidal anti-inflammatory drugs. | ||||
| * P value for mixed model analysis (group-time interaction). | ||||
| † P <.05 for difference between groups during the study period. | ||||
| ‡ P <.05 for comparison of baseline vs study period. | ||||
| Antibiotics | ||||
| Intervention group | 27.19 (2.27) | 25.04 (2.29) | −2.15 | .69 |
| Control group | 29.92 (2.18) | 28.88 (2.26) | −1.04 | |
| Antidepressants | ||||
| Intervention group | 60.37 (2.87) | 50.59 (2.83) | −9.78†‡ | .06 |
| Control group | 62.05 (2.85) | 60.22 (2.93) | −1.83 | |
| Rhinitis medications | ||||
| Intervention group | 69.11 (2.21) | 66.58 (2.07) | −2.53 | .24 |
| Control group | 62.27 (2.85) | 64.48 (2.10) | 2.21 | |
| GERD medications | ||||
| Intervention group | 96.08 (6.21) | 84.38 (6.04) | −11.70† | .10 |
| Control group | 104.73 (6.25) | 108.83 (5.93) | 4.10 | |
| Asthma medications | ||||
| Intervention group | 62.65 (4.54) | 49.92 (4.55) | −12.73‡ | .25 |
| Control group | 64.84 (4.47) | 61.73 (4.58) | −3.11 | |
| Diabetes medications | ||||
| Intervention group | 53.15 (4.74) | 42.09 (5.14) | −11.06 | .94 |
| Control group | 59.95 (4.55) | 48.22 (4.83) | −11.73 | |
| Antihypertension medications, diuretics | ||||
| Intervention group | 23.52 (1.19) | 18.36 (1.16) | −5.16†‡ | .30 |
| Control group | 25.83 (1.18) | 22.65 (1.15) | −3.18‡ | |
| Lipid-lowering agents | ||||
| Intervention group | 73.06 (4.07) | 66.55 (3.95) | −6.51 | .49 |
| Control group | 74.85 (3.76) | 62.98 (3.85) | −11.87‡ | |
| Triptans and headache medications | ||||
| Intervention group | 94.81 (9.60) | 67.02 (9.22) | −27.79‡ | .01 |
| Control group | 69.26 (9.69) | 88.95 (9.64) | 19.69 | |
| COX-2 inhibitors and NSAIDs | ||||
| Intervention group | 25.51 (4.69) | 29.53 (4.64) | 4.02 | .59 |
| Control group | 33.00 (4.63) | 40.53 (4.54) | 7.53 | |
| Totals for high-cost drug categories | ||||
| Intervention group | 49.94 (2.05) | 45.03 (2.03) | −4.91†‡ | .06 |
| Control group | 52.12 (2.03) | 51.63 (2.02) | −0.49 | |