Model Performance in the Validation Cohort
| Outcome Predicted (Subjects) | Number of Patients | Patient With Outcome No. (%) | C-Statistic |
|---|---|---|---|
| * Good predictive model (defined a priori as having a C -statistic > 0.70)39,40 | |||
| Myocardial infarction (all patients) | 2,912 | 198 (6.8) | 0.76* |
| First myocardial infarction (patients with no previous myocardial infarction) | 2,522 | 112 (4.4) | 0.62 |
| Stroke (all patients) | 2,912 | 514 (18) | 0.79* |
| First stroke (patients with no previous stroke) | 2,612 | 317 (12) | 0.67 |
| Myocardial infarction or stroke (all patients) | 2,912 | 640 (22) | 0.78* |
| First myocardial infarction or stroke (patients with no previous myocardial infarction or stroke) | 2,326 | 334 (14) | 0.65 |
| First ischemic heart disease (patients with no previous ischemic heart disease) | 1,811 | 194 (11) | 0.63 |
| First heart failure (patients with no previous heart failure) | 2,481 | 332 (13) | 0.68 |
| First chronic renal insufficiency (patients with no previous renal insufficiency) | 2,281 | 151 (6.6) | 0.81* |
| All-cause mortality (all patients) | 2,912 | 378 (13) | 0.78* |