Table 4.

Probably Ineffective Nonsurgical Treatment of Carpal Tunnel Syndrome

TreatmentEvidenceFindings
NSAID = nonsteriodal anti-inflammatory drug; RCT = randomized controlled trial.
NSAID2 RCTs16,18No significant reduction in symptom measures
Diuretic1 RCT16No significant reduction in symptom measures from baseline to 4th week assessment
Pyridoxine2 RCTs27,28Reduced finger swelling and discomfort after movement but no difference in nocturnal pain, numbness, Phalen’s or Tinel’s signs or nerve conduction studies in one study, and no significant difference in the other study
Chiropractic treatment1 RCT18No significant reduction in symptom measures
Magnet therapy1 RCT15No difference in effect between magnet and placebo