Table 1.

Dichotomous Univariable Predictors of Adverse Vascular Events

			Coefficients for Univariable Proportional Hazards Regression
Variable	No.	(%)	MI	CVA	MI or CVA	IHD	HF	CRI	Death
MI = myocardial infarction, CVA = stroke (cerebrovascular accident), IHD = ischemic heart disease, HF = heart failure, CRI = chronic renal insufficiency.
* P ≤.001.
† P ≤.05.
‡ P ≤.01.
Patient Characteristics
Female sex	4028	(69)	−0.368*	−0.138^†	−0.202*	−0.224^†	0.005	−0.458*	−0.319^‡
Black race	3659	(63)	−0.362*	−0.032	−0.113^†	−0.413*	−0.408	0.278^†	0.031
Smoker	1344	(23)	0.599*	0.383*	0.439*	0.100	0.340*	0.192	0.535*
Vascular events prior to index visit
Ischemic heart disease	2,209	(38)	1.402*	0.632*	0.832*	—	0.615*	0.483*	0.635*
Renal failure	1,255	(22)	0.823*	0.773*	0.773*	0.547*	0.640*	—	1.036
Heart failure	895	(15)	1.231*	0.790*	0.941*	0.742*	—	0.979*	1.307*
Myocardial infarction	814	(14)	2.009*	0.868*	1.241*	—	0.924*	0.600*	1.034*
Stroke	563	(10)	0.720*	2.472*	2.141*	0.486^‡	0.608*	0.162*	0.827*
Myocardial infarction or stroke	1,198	(21)	1.733*	1.693*	1.777*	—	0.853*	0.513*	1.094*
Active drug therapy at index visit
Diuretics	2,493	(43)	0.405*	0.785*	0.314*	0.192	0.292*	0.530*	0.417*
Aspirin	1,306	(22)	1.254*	1.174*	1.217*	0.560*	0.794*	0.568*	0.713*
Calcium channel blockers	1,867	(32)	0.698*	0.495*	0.530*	0.124	0.526*	0.548*	0.256^‡
Ace inhibitors	1,706	(29)	0.538*	0.441*	0.475*	0.265^†	0.508*	0.558*	0.499*
Nitrates	839	(14)	1.729*	0.785*	1.083*	—	0.819*	0.842*	0.020
Beta blockers	711	(12)	0.726*	0.381*	0.494*	0.166	0.338*	0.313^†	−0.149
Insulin	581	(10)	0.729*	0.502*	0.587*	0.801*	1.020*	1.739*	0.710*
Oral antidiabetic drugs	565	(10)	0.541*	0.454*	0.488*	0.394^‡	0.515*	0.884*	0.195
Statin antilipemic drug	216	(4)	0.908*	0.600*	0.622*	0.623^†	0.476^‡	0.657^‡	0.613^‡
Alpha blockers	147	(2)	0.305	0.422^‡	0.298	0.366	0.569^‡	0.944*	0.380
Warfarin	127	(2)	1.483*	0.796*	1.040*	1.050^‡	0.939*	0.724^†	1.108*
Previous diagnoses recorded on or before index visit
Diabetes mellitus	1,933	(33)	0.899*	0.648*	0.713*	0.625*	0.788*	1.346*	0.861*
Obesity	1,508	(26)	0.090	0.029	0.058	0.032	0.258^‡	0.385*	0.010
Alcohol abuse	741	(13)	0.263^†	0.328*	0.286*	0.177	0.065	0.413^‡	0.545*
Chronic obstructive lung disease	573	(10)	0.885*	0.724*	0.796*	0.573*	0.783*	0.337	1.058*
Renal insufficiency	369	(6)	1.042*	1.060*	1.050*	0.514^†	0.778*	3.075*	1.496*
Hypothyroidism	368	(6)	0.566*	0.397*	0.418*	0.050	0.298^†	0.296	0.187
Peripheral arterial disease	257	(4)	0.998*	0.768*	0.811*	0.960*	0.703*	1.084*	1.211*