Table 1.

Traditional Distinctions Between Research and Quality Improvement

CharacteristicResearchQuality Improvement
IntentDiscoveryApplication
Impetus driven byCurrent state of knowledgeNeeds of end users
CircumstanceOptionalOften required
FoundationTheory-drivenApplication-driven
PhilosophyNaturalismPragmatism
ConductPreplannedIterative
ConsentRequiredImplied
Source of dataMultiple organizationsSingle organization
AudienceMultiple organizationsSingle organization
Deviation from usual practiceSignificantMinimal
Unit of analysisPatient or clinicianClinician or practice
Outcome measuresStudy specific/additionalRoutinely collected data
Evaluation criteriaScientific rigorProcess validity
Benefit to participantsLittle direct benefit to most participantsDirect benefit to most participants
Level of risk/burden to participantsHigherLower
TimelineYearsWeeks or months