Prognostic Variables and Patient Recovery: Results of Cox Proportional Hazard Regression Analyses (N = 300)
| Bivariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
| Prognostic Variable | HR | 95% CI | P Value | HR | 95% CI | P Value |
| * HR = hazard ratio (ratio of the instantaneous recovery rate with and without the prognostic variable; HR <1 means slower recovery when that variable is present at first examination); CI = confidence interval. | ||||||
| † Results of the stepwise (backward and forward) Cox multiple regression analysis. The variables included in the analysis were sex, unilateral facial pain, reduced productivity, and a general feeling of illness. | ||||||
| ‡ n = 218. | ||||||
| Placebo treatment | 0.97 | 0.76–1.24 | .80 | – | – | |
| Age older than mean (37 years) | 0.86 | 0.66–1.11 | .23 | – | – | |
| Female sex | 1.20 | 0.93–1.54 | .16 | Not selected† | ||
| Purulent rhinorrhea | 1.09 | 0.84–1.40 | .52 | – | – | |
| Postnasal drip | 0.90 | 0.70–1.16 | .42 | – | – | |
| Temperature ≥37.5°C | 0.86 | 0.60–1.23 | .40 | – | – | |
| Complaints ≥7 days | 0.94 | 0.73–1.21 | .65 | – | – | |
| Biphasic illness | 0.92 | 0.71–1.18 | .49 | – | – | |
| Pain on bending | 0.97 | 0.75–1.27 | .85 | – | – | |
| Unilateral facial pain | 0.76 | 0.59–0.98 | .03 | Not selected† | ||
| Pain in upper teeth | 0.82 | 0.59–1.14 | .24 | – | – | |
| Fatigue | 0.83 | 0.64–1.07 | .15 | – | – | |
| Reduced productivity | 0.75 | 0.59–0.97 | .03 | 0.77 | 0.60–0.99 | .04† |
| General feeling of illness | 0.67 | 0.52–0.87 | .002 | 0.68 | 0.53–0.88 | .003† |
| Abnormal radiograph‡ | 1.02 | 0.76–1.37 | .90 | – | – | |
| Clinical sum score ≥4 | 0.76 | 0.60–0.98 | .04 | Not selected† | ||