Table 2.

Prognostic Variables and Patient Recovery: Results of Cox Proportional Hazard Regression Analyses (N = 300)

Bivariate AnalysisMultivariate Analysis
Prognostic VariableHR95% CIP ValueHR95% CIP Value
* HR = hazard ratio (ratio of the instantaneous recovery rate with and without the prognostic variable; HR <1 means slower recovery when that variable is present at first examination); CI = confidence interval.
† Results of the stepwise (backward and forward) Cox multiple regression analysis. The variables included in the analysis were sex, unilateral facial pain, reduced productivity, and a general feeling of illness.
‡ n = 218.
Placebo treatment0.970.76–1.24.80
Age older than mean (37 years)0.860.66–1.11.23
Female sex1.200.93–1.54.16Not selected
Purulent rhinorrhea1.090.84–1.40.52
Postnasal drip0.900.70–1.16.42
Temperature ≥37.5°C0.860.60–1.23.40
Complaints ≥7 days0.940.73–1.21.65
Biphasic illness0.920.71–1.18.49
Pain on bending0.970.75–1.27.85
Unilateral facial pain0.760.59–0.98.03Not selected
Pain in upper teeth0.820.59–1.14.24
Reduced productivity0.750.59––0.99.04
General feeling of illness0.670.52–0.87.0020.680.53–0.88.003
Abnormal radiograph1.020.76–1.37.90
Clinical sum score ≥40.760.60–0.98.04Not selected