Table 5.

Summary of Primary Studies of the Accuracy of Computed Tomography for the Diagnosis of Pulmonary Embolism

Author, Year	Main Inclusion Criteria	No. of CT Detectors	No. of Patients	Most Distal Arterial Level Interpreted	PE Prevalence %	Sensitivity % (95% CI)	Specificity % (95% CI)
CT = computed tomography; PE = pulmonary embolism; CI = confidence interval; V/Q = ventilation-perfusion ICU = intensive care unit.
Remy-Jardin et al,⁷⁰ 1992	Clinically suspected PE or unexplained chest radiograph abnormality	1	42	Segmental	43	100 [81–100]	96 [79–100]
Blum et al,⁷¹ 1994	Clinical suspicion of massive PE	1	10	Segmental	70	100 [59–100]	100 [29–100]
Goodman et al,⁷² 1995	Nondiagnostic V/Q scan	1	20	Subsegmental	55	64 [31–89]	89 [52–100]
Remy-Jardin et al,⁷³ 1996	Referral for pulmonary arteriography	1	75	Segmental	57	91 [78–97]	78 [60–91]
Christiansen, 1997⁷⁴	High clinical suspicion of PE	1	70	Segmental	27	89 [67–99]	96 [87–100]
Drucker et al,⁷⁵ 1998	Referral for pulmonary arteriography	1	47	Segmental	32	60 [32–84]	81 [64–93]
Qanadli et al,⁷⁶ 2000	Referral to the radiology department	2	157	Subsegmental	39	90 [80–96]	94 [87–98]
Velmahos et al,⁷⁷ 2001	Surgical ICU patients with explicitly defined clinical 3 ndings associated with PE	1	22	Subsegmental	50	45 [17–77]	82 [48–98]
Winer-Muram et al,⁶⁹ 2004 (multidetector CT)	Emergency department and inpatients referred for pulmonary arteriography	4	93	Subsegmental	19	100 [81–100]	89 [80–95]