Table 5.

Summary of Primary Studies of the Accuracy of Computed Tomography for the Diagnosis of Pulmonary Embolism

Author, YearMain Inclusion CriteriaNo. of CT DetectorsNo. of PatientsMost Distal Arterial Level InterpretedPE Prevalence %Sensitivity % (95% CI)Specificity % (95% CI)
CT = computed tomography; PE = pulmonary embolism; CI = confidence interval; V/Q = ventilation-perfusion ICU = intensive care unit.
Remy-Jardin et al,70 1992Clinically suspected PE or unexplained chest radiograph abnormality142Segmental43100 [81–100]96 [79–100]
Blum et al,71 1994Clinical suspicion of massive PE110Segmental70100 [59–100]100 [29–100]
Goodman et al,72 1995Nondiagnostic V/Q scan120Subsegmental5564 [31–89]89 [52–100]
Remy-Jardin et al,73 1996Referral for pulmonary arteriography175Segmental5791 [78–97]78 [60–91]
Christiansen, 199774High clinical suspicion of PE170Segmental2789 [67–99]96 [87–100]
Drucker et al,75 1998Referral for pulmonary arteriography147Segmental3260 [32–84]81 [64–93]
Qanadli et al,76 2000Referral to the radiology department2157Subsegmental3990 [80–96]94 [87–98]
Velmahos et al,77 2001Surgical ICU patients with explicitly defined clinical 3 ndings associated with PE122Subsegmental5045 [17–77]82 [48–98]
Winer-Muram et al,69 2004 (multidetector CT)Emergency department and inpatients referred for pulmonary arteriography493Subsegmental19100 [81–100]89 [80–95]