One-Way Sensitivity Analyses for a Cost-Effectiveness Analysis of Treatment Strategies for Acute Otitis Media: 7 to 10 Days of Amoxicillin Compared With Delayed Prescription
| Variable | Variable Range | Effect on ICUR |
|---|---|---|
| ICUR = incremental cost utility ratio (cost-effectiveness ratio in dollars per quality-adjusted life-year); GI = gastrointestinal; DP = delayed prescription. | ||
| * Dominant: option was more effective and less costly than comparative option. | ||
| Amoxicillin cost, $ | 7.74–14.95 | 54,200–68,000 |
| Non–health care cost, $ | 7.54–30.16 | 54,500–62,200 |
| Office consultation cost, $ | 17.12–68.46 | 43,300–85,600 |
| Work loss cost, $ | 46–182 | 58,100–56,000 |
| Probability of clinical failure—routine amoxicillin | 0.044–0.078 | 42,000–80,300 |
| Probability of GI adverse effects from antibiotic | 0.042–0.156 | 49,200–68,900 |
| Probability of nonattendance—routine amoxicillin | 0–0.076 | 71,600–53,600 |
| Probability of nonattendance—DP | 0–0.448 | Dominant* if probability is <0.23; 33,000–89,400 if probability is >0.23 |
| Probability of prescription redemption—DP | 0.172–0.308 | 142,000–33,000 |
| Utility of a day of treatment failure | 0.646–0.794 | 40,500–98,600 |