Table 1.

Effect of Multiple Factors on Harm or Benefit of Direct-to-Consumer (DTC) Ads

FactorEffect on Ratio of DTC Harm to Benefit
Condition severity
    Serious↑ potential benefit
    Mild↑ risk of harm
Prevalence of condition
    Rare↑ risk of harm
    Common↓ risk of harm
Effectiveness of treatment
    High↑ potential for benefit
    Low↓ potential for benefit
Side effects of treatment
    Severe and/or common↑ risk of harm
    Mild and/or rare↓ risk of harm
Rate of treatment
    Undertreated↑ potential for benefit
    Not undertreated↑ risk of harm