Dementia Risk in Relation to SMC in Combination With Either the MMSE-5 or VAT
| Variable | No. of Dementia Cases/No. at Risk (%) | HR (95% CI) | P Value | Adjusted HR (95% CI)a | P Value |
|---|---|---|---|---|---|
| No SMC and optimal MMSE-5b | 48/1,176 (4) | 1 (reference) | |||
| No SMC and imperfect MMSE-5 | 98/1,645 (6) | 1.52 (1.08-2.15) | .017 | 1.41 (1.0-2.0) | .056 |
| SMC and optimal MMSE-5 | 11/210 (5) | 1.33 (0.69-2.56) | .394 | 1.32 (0.69-2.55) | .401 |
| SMC and imperfect MMSE-5 | 75/391 (19) | 5.48 (3.82-7.88) | <.001 | 5.06 (3.5-7.3) | <.001 |
| No SMC and optimal VATc | 77/2,060 (4) | 1 (reference) | |||
| No SMC and imperfect VAT | 68/749 (9) | 2.62 (1.89-3.63) | <.001 | 2.56 (1.84-3.57) | <.001 |
| SMC and optimal VAT | 29/373 (8) | 2.25 (1.45-3.45) | <.001 | 2.33 (1.52-3.58) | <.001 |
| SMC and imperfect VAT | 55/223 (25) | 7.74 (5.47-10.94) | <.001 | 7.15 (5.01-10.19) | <.001 |
HR = hazard ratio; MMSE-5 = Mini-Mental State Examination, item 5 (delayed recall); SMC = subjective memory complaints; VAT = Visual Association Test.
↵a Adjusted for age and educational level.
↵b For 32 participants, SMC, MMSE-5, or both, was missing.
c For 49 participants, SMC, VAT, or both, was missing.