Dementia Risk in Relation to SMC and Scores on the MMSE-5 and VAT
| Variable | No. Dementia Cases/No. at Risk (%) | HR (95% CI) | P Value | Adjusted HR (95% CI)a | P Value |
|---|---|---|---|---|---|
| No SMC | 146/2,822 (5) | 1 (reference) | |||
| SMC | 86/601 (14) | 3.01 (2.31-3.94) | <.001 | 2.97 (2.27-3.9) | <.001 |
| Optimal MMSE-5 (3 points) | 59/1,403 (4) | 1 (reference) | |||
| Imperfect MMSE-5 (<3 points) | 174/2,050 (8) | 2.14 (1.59-2.87) | <.001 | 1.98 (1.47-2.67) | .007 |
| Optimal VAT (6 points) | 106/2,454 (4) | 1 (reference) | |||
| Imperfect VAT (<6 points) | 124/982 (13) | 3.19 (2.46-4.13) | <.001 | 3.04 (2.33-3.95) | <.001 |
HR = hazard ratio; MMSE-5 = Mini-Mental State Examination, item 5 (delayed recall); SMC = subjective memory complaints; VAT = Visual Association Test.
↵a Adjusted for age and educational level.