All-Cause Mortality (n=355 Deaths) | Cardiovascular Mortality (n =169 Deaths) | |||||
---|---|---|---|---|---|---|
Characteristic | HR | 95% CI | PValue | HR | 95% CI | PValue |
HR = hazard ratio; CI = confidence interval. | ||||||
a Crude/unadjusted hazard ratio (estimated using univariate Cox regression model) for white coat hypertension vs sustained hypertension. | ||||||
b Adjusted hazard ratios (estimated using multivariate Cox regression model). Values were adjusted for blood pressure category, sex, age (continuous), smoking, antihypertensive medication use, and clustering at the practice level. Reference groups were as follows: blood pressure category: sustained hypertension; sex: female; smoking: never smokers; and antihypertensive medication use: taking medication. | ||||||
White coat hypertension | ||||||
Crudea | 0.43 | 0.30–0.60 | <.001 | 0.43 | 0.29–0.63 | <.001 |
Adjustedb | 0.64 | 0.42–0.97 | .04 | 0.63 | 0.39–1.02 | .058 |
Male sexb | 1.66 | 1.34–2.06 | <.001 | 1.95 | 1.47–2.59 | <.001 |
Age (5-year increments)b | 1.61 | 1.52–1.71 | <.001 | 1.63 | 1.50–1.77 | <.001 |
Smoker or exsmokerb | 1.39 | 1.16–1.67 | <.001 | 1.25 | 0.95–1.64 | .12 |
Not taking antihypertensive medicationb | 0.75 | 0.61–0.93 | .008 | 0.72 | 0.56–0.94 | .01 |