Table 3.

Measures of Psychological Symptoms (4DSQ) and Sleep (SCL-90) in the 4 Subgroups at Baseline and After 12 Months

Baseline12 Months
Measure by SubgroupScore, Mean (SD)Elevated Score,aNo. (%)Score, Mean (SD)Elevated Score,aNo. (%)Mean Change in Score (95% CI)
4DSQ = Four-Dimensional Symptoms Questionnaire; SCL-90 = Symptom Checklist 90; CI = confidence interval.
Note: 123 patients had a chronic course, 83 had a fast recovery, 122 had a slow recovery, and 154 had recurrent fatigue.
a Cutoffs for elevations of 4DSQ scores and SCL-90 scores are as indicated in Table 2.
b Not significant.
Distress
    Chronic course15.8 (7.3)93 (76)13.1 (7.7)70 (58)2.6 (1.4–3.9)
    Fast recovery9.5 (6.4)33 (40)3.7 (3.9)6 (7.3)5.8 (4.5–7.2)
    Slow recovery13.8 (7.3)78 (64)7.3 (5.6)31 (26)6.5 (5.3–7.7)
    Recurrent fatigue12.7 (6.9)90 (59)9.1 (6.2)56 (38)3.6 (2.5–4.8)
Somatization
    Chronic course13.6 (6.9)79 (64)11.6 (6.6)68 (57)2.1 (1.1–3.0)
    Fast recovery8.1 (5.0)21 (25)3.8 (3.6)4 (4.9)4.3 (3.3–5.2)
    Slow recovery11.2 (5.4)63 (52)6.7 (5.4)21 (17)4.5 (3.7–5.4)
    Recurrent fatigue10.5 (5.6)67 (44)7.9 (5.3)43 (29)2.6 (1.7–3.4)
Depression
    Chronic course2.6 (3.2)46 (37)2.2 (3.0)43 (36)0.41 (–0.1 to 0.9)b
    Fast recovery0.9 (2.1)13 (16)0.1 (0.5)1 (1.2)0.83 (0.4–1.3)
    Slow recovery1.4 (2.2)28 (23)0.5 (1.3)8 (6.6)0.82 (0.5–1.2)
    Recurrent fatigue1.3 (2.0)29 (19)0.8 (2.0)16 (11)0.48 (0.2–0.8)
Anxiety
    Chronic course3.4 (4.3)20 (16)2.9 (3.9)13 (11)0.53 (−0.1 to 1.2)b
    Fast recovery1.1 (1.9)2 (2.4)0.4 (1.0)0 (0)0.66 (0.3–1.0)
    Slow recovery2.6 (3.4)13 (11)1.4 (2.3)4 (3.3)1.20 (0.7–1.7)
    Recurrent fatigue2.3 (3.5)15 (9.7)1.8 (3.4)8 (5.4)0.50 (0.0–1.0)
Sleep
    Chronic course7.4 (3.4)80 (66)7.5 (3.1)90 (73)0.16 (−0.6 to 0.3)b
    Fast recovery6.0 (2.8)43 (52)5.1 (2.1)36 (43)0.88 (0.2–1.5)
    Slow recovery7.7 (3.3)91 (75)6.2 (2.4)67 (55)1.50 (1.0–2.0)
    Recurrent fatigue6.7 (3.0)96 (62)6.5 (2.6)91 (59)0.25 (−0.2 to 0.7)b