PSA | >4 ng/mL | Endoscopy | Biopsy | Prostatectomy |
| | | Cystourethroscopy | |
| | | Cystoscopy | |
| | | Cystopanendoscopy | |
| | | Lymphadenectomy | |
| | | Ureterogram | |
| | | Transurethral resection of the prostate (TURP) | |
DRE | One or more of the following findings: | As for PSA | As for PSA | As for PSA |
| Nodularity | | | |
| Induration | | | |
| Asymmetry | | | |
| Loss of anatomic landmarks | | | |
CA-125 | >35 U/mL | Colonoscopy | Biopsy | Hysterectomy |
| | | Culdocentesis | Laparotomy |
| | | Hysteroscopy | Omentectomy |
| | | Intra-abdominal washings | Oophorectomy |
| | | Laparoscopy | Ovarian lymphadenectomy (with laparotomy) |
| | | Paracentesis | |
TVU | One or more of the following findings: | As for CA-125 | As for CA-125 | As for CA-125 |
| Ovary or cyst >10 cca | | | |
| Solid area or papillary projection extending into the cavity of a cystic ovarian tumor of any size | | | |
| Mixed (solid/cystic) component within a cystic ovarian tumor | | | |
CXR | One or more of the following findings: | Bronchoscopy | Biopsy | Lung resection |
| Nodule | | Lymphadenectomy | Thoracotomy |
| Mass | | Mediastinoscopy | |
| Hilar or mediastinal lymph node enlargement | | Thoracoscopy | |
| Major atelectasis or lobar collapse | | Transbronchial aspiration | |
| Infiltrate, consolidation, or alveolar opacity | | Transthoracic aspiration | |
FSG | One or more of the following findingsb: | Colonoscopy (with- out biopsy) | Biopsy | Colon resection |
| Rectal nodule(s) | | Cystoscopy | Hemicolectomy |
| Rectal and/or colon mass(es) | Endoscopy | Lymphadenectomy | Laparotomy |
| Colon polyp(s) | Rigid sigmoidoscopy | | |