M-3 Psychometrics for Specific Diagnoses and for Any Diagnosis by MINI (n = 647)
Diagnosis by MINI | |||||
---|---|---|---|---|---|
Test Result | Depression (n=142) | Bipolar (n=60) | Anxiety (n=182) | PTSD (n=41) | Any Diagnosis (n=224) |
CI=confidence interval; LR = likelihood ratio; M-3 = My Mood Monitor checklist; MINI = Mini International Neuropsychiatric Interview; PTSD=post-traumatic stress disorder. | |||||
a If any diagnosis cut-off score was met, the screen was considered positive. | |||||
b Number with a positive screen and who have that diagnosis by MINI/total number with a positive screen by M-3. | |||||
c Number with a negative screen and who do not have that diagnosis by MINI/total number with a negative screen by M-3. | |||||
M-3 subscore cutoff (≥) | 5 | 2 | 3 | 2 | Any positive screena |
Question No. | 1–7 | 20–23 | 8–19 | 13–16 | 1–23 |
Sensitivity (95% CI) | 0.84 (0.77–0.89) | 0.88 (0.77–0.95) | 0.82 (0.75–0.87) | 0.88 (0.74–0.96) | 0.83 (0.77–0.88) |
Specificity (95% CI) | 0.80 (0.76–0.83) | 0.70 (0.66–0.74) | 0.78 (0.74–0.81) | 0.76 (0.73–0.80) | 0.76 (0.72–0.80) |
Positive LR (95% CI) | 4.19 (3.47–5.06) | 2.94 (2.53–3.44) | 3.65 (3.05–4.39) | 3.69 (3.08–4.44) | 3.48 (2.90–4.16) |
Negative LR (95% CI) | 0.20 (0.14–0.29) | 0.17 (0.08–0.33) | 0.23 (0.17–0.32) | 0.16 (0.07–0.36) | 0.22 (0.17–0.30) |
Positive M-3 screen, % | 34 | 35 | 39 | 28 | 44 |
Diagnosed by MINI, % | 22 | 9 | 28 | 6 | 35 |
Positive predictive value (95% CI) [n/n]b | 0.54 (0.47–0.61) [119/220] | 0.23 (0.18–0.29) [53/229] | 0.59 (0.53–0.65) [149/253] | 0.20 (0.15–0.27) [36/180] | 0.65 (0.59–0.70) [186/287] |
Negative predictive value (95% CI) [n/n]c | 0.95 (0.92–0.96) [404/427] | 0.98 (0.96–0.99) [411/418] | 0.92 (0.88–0.94) [361/394] | 0.99 (0.97–1.0) [462/467] | 0.89 (0.86–0.92) [322/360] |