Outcomes of the DeLLITE Trial: Function, Mood, Quality of Life, Falls, and Physical Activity
| Change | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Outcome | Baseline | 0–6 Mo | 6 Mo | 6–12 Mo | 12 Mo | Time-Group Interaction F Statistic | Time-Group Interaction P Valuea | Time F Statistic | Time P Valuea |
| GDS-15 = Geriatric Depression Scale; MHC = SF-36 MHC = Medical Outcomes Study Short Form 36-item mental health component subscale; NEADL = Nottingham Extended Activities of Daily Living Scale; SF-36 PHC = Medical Outcomes Study Short Form 36-item physical health component subscale; SPPB = Short physical performance battery; | |||||||||
| a P values are for generalized linear mixed models using time as a repeated measure. | |||||||||
| b Scores range from 0 to 22; higher score indicates greater function. | |||||||||
| c Scores range from 0 to 12; higher score indicates better function. | |||||||||
| d Scores range from 0 to 15; lower score indicates better mood. | |||||||||
| e Scores range from 0 to 100; higher score indicates better physical health-related quality of life. | |||||||||
| f Scores range from 0 to 100; higher score indicates better mental health-related quality of life. | |||||||||
| Function | |||||||||
| NEADL score, mean (SD)b | 0.00 | .997 | 6.19 | .003 | |||||
| Physical activity | 18.2 (0.3) | −0.1 (0.2) | 18.0 (0.3) | −0.2 (0.1) | 17.8 (0.3) | ||||
| Social control | 17.9 (0.4) | −0.0 (0.2) | 17.9 (0.4) | −0.2 (0.2) | 17.8 (0.4) | ||||
| SPPB score, mean (SD)c | 1.30 | .274 | 1.38 | .255 | |||||
| Physical activity | 7.5 (0.3) | 0.3 (0.2) | 7.8 (0.3) | −0.2 (0.2) | 7.5 (0.3) | ||||
| Social control | 7.6 (0.3) | −0.0 (0.2) | 7.6 (0.3) | −0.2 (0.2) | 7.5 (0.3) | ||||
| Mood | |||||||||
| GDS-15 score, mean (SD)d | 0.09 | .916 | 18.49 | <.001 | |||||
| Physical activity | 3.4 (0.3) | −0.9 (0.2) | 2.4 (0.2) | −0.0 (0.2) | 2.4 (0.2) | ||||
| Social control | 4.0 (0.3) | −0.9 (0.3) | 3.1 (0.3) | −0.1 (0.2) | 2.8 (0.3) | ||||
| GDS-15 score >4, No. (%) | 1.32 | .269 | 4.30 | .015 | |||||
| Physical activity | 21 (21.6) | (−8.9) | 12 (12.8) | (4.3) | 16 (17.0) | ||||
| Social control | 35 (36.5) | (−9.3) | 25 (27.2) | (−7.2) | 18 (20.7) | ||||
| Health-related quality of life | |||||||||
| SF-36 PHC score, mean (SD)e | 2.73 | .068 | 0.27 | .761 | |||||
| Physical activity | 39.0 (1.2) | 0.6 (0.9) | 39.5 (1.2) | −1.2 (0.8) | 38.3 (1.2) | ||||
| Social control | 39.3 (1.1) | −1.5 (0.9) | 37.9 (1.3) | 0.9 (0.7) | 39.4 (1.2) | ||||
| SF-36 MHC score, mean (SD)f | 1.44 | .240 | 20.36 | <.001 | |||||
| Physical activity | 51.2 (0.9) | 3.6 (0.9) | 54.7 (0.7) | 0.7 (0.7) | 55.4 (0.7) | ||||
| Social control | 48.7 (1.0) | 4.5 (1.0) | 53.7 (0.9) | −1. 6 (0.9) | 52.7 (0.9) | ||||
| Physical activity | |||||||||
| Auckland Heart Study Physical Activity Questionnaire, walking, mean (SD), min/wk | 2.96 | .054 | 1.82 | .165 | |||||
| Physical activity | 121.0 (13.8) | 41.2 (15.8) | 162.3 (16.0) | −33.5 (16.4) | 128.8 (14.0) | ||||
| Social control | 124.5 (16.1) | −13.3 (16.1) | 115.3 (13.2) | 3.5 (13.9) | 119.5 (16.1) | ||||
| Auckland Heart Study Physical Activity Questionnaire, moderate to vigorous, mean (SD), min/wk | 0.74 | .479 | 6.43 | .002 | |||||
| Physical activity | 315.4 (43.5) | −13.0 (41.6) | 302.3 (33.9) | −38.8 (35.5) | 263.6 (38.2) | ||||
| Social control | 379.0 (51.0) | −70.0 (43.6) | 309.0 (38.2) | −87.9 (27.4) | 221.1 (31.7) | ||||