Table 3.

Methodologic Quality of Studies, Based on the Newcastle-Ottawa Scale (N = 11)

SelectionComparabilityExposure
StudyAdequate Definition of CasesRepresentativeness of CasesSelection of ControlsDefinition of ControlsControl for Important Factor or Additional FactorAscertain ment of Exposure (Blinding)Same Method of Ascertainment for SubjectsNonresponse RateTotal Scorea
a Possible total scores range from 0 (lowest quality) to 9 (highest quality). Studies included in the meta-analysis were defined as high-quality if their total score was greater than 7.
Case-control (n=8)
Grisso et al,49 1997100020104
Vestergaard et al,39 2006011020116
Yang et al,22 2006011020116
Kaye and Jick,42 2008011120117
Targownik et al,23 2008011120117
Corley et al,50 2010111121119
Chiu et al,53 2010111121119
Pouwels et al,52 2011011121118
Cohort (n=3)
Yu et al,40 2008111021107
Roux et al,41 2009111121108
Gray et al,51 2010111121108