Table 6

Mean Differences in DHI Scores and Odds Ratios to Develop Substantial Dizziness-Related Impairment After 10 Years for the Primary Cause of Dizziness (N = 103)

Primary Cause of DizzinessNo. of PersonsBaseline Values Unadjusted MD in DHI Score (95% CI)Adjusted MD in DHI Score (95% CI)aUnadjusted OR for DHI ≥30, OR (95% CI)Adjusted OR for DHI ≥30, OR (95% CI)a
Mean DHI (SD)DHI ≥30, %
Cardiovascular5028.8 (17.4)42.0ReferenceReferenceReferenceReference
Peripheral vestibular2334.1 (18.1)56.52.60 (−6.67 to 11.87)3.10 (−5.14 to 11.34)1.33 (0.56-3.20)1.46 (0.52-4.08)
Psychiatric1238.5 (23.2)58.33.39 (−8.44 to 15.22)1.31 (−9.43 to 12.06)1.22 (0.43-3.44)1.01 (0.32-3.25)
Other causesb1830.6 (17.8)50.0−1.00 (−11.11 to 9.12)3.76 (−5.24 to 12.76)1.22 (0.48-3.12)1.63 (0.61-4.30)
  • DHI = dizziness handicap inventory; MD = mean difference; OR = odds ratio; PRIME-MD PHQ = Primary Care Evaluation of Mental Disorders Patient Health Questionnaire.

  • a Adjusted for age, sex, ethnicity, level of education, preexistent cardiovascular disease and/or stroke, diabetes, polypharmacy (defined as >5 types of daily medication), an anxiety or depressive disorder according to the PRIME-MD PHQ, and the number of assigned dizziness subtypes.

  • b Locomotor disease (n = 0), neurologic disease (excluding cerebrovascular disease) (n = 2), adverse drug effect (n = 5), metabolic or endocrine conditions (n = 0), impaired vision (n = 1), other causes (n = 1), and unclear cause (n = 9).