Table 5.

Frequency of Adverse Events in Placebo-Controlled Studies of Pramlintide in Type 1 Diabetes

TrialAny Nausea %Severe Nausea %Any Anorexiaaor Reduced Appetite %Severe Anorexia or Reduced Appetite %Any Vomiting %Severe Vomiting %
aAnorexia was defined as decreased appetite, early satiety or gastric fullness, loss of appetite, or no appetite.
bThe rate of 95.1% occurred in persons in the pramlintide 30-μg group.
Edelman et al, 20065
Whitehouse et al, 200210
Ratner et al, 20047