Table 1

Baseline Characteristics of the Cohort of Patients Studied

CharacteristicOverall Population (n=447)Men (n=201)Women (n=246)P Value
Age, mean (SD), y52.4 (9.6)50.9 (9.8)53.6 (9.2)<.01
SBP, mean (SD), mm Hg132.0 (17.8)130.7 (16.6)133.1 (18.7).147
DBP, mean (SD), mm Hg82.1 (10.2)82.5 (10.8)81.7 (9.7).466
Arterial hypertension, n (%)122 (27.3)51 (25.4)71 (28.9).410
Total cholesterol, mean (SD), mg/dL238.9 (34.7)239.3 (34.1)238.7 (35.2).861
HDL cholesterol, mean (SD), mg/dL53.6 (15.7)47.3 (13.2)58.7 (15.7)<.001
LDL cholesterol, mean (SD), mg/dL160.4 (33.2)161.9 (31.9)159.1 (34.2).870
Triglycerides, median (SD), mg/dLa107.0 (79.0–149.5)131.0 (96.3–177.8)96.0 (71.5–125.5)<.001
BMI, mean (SD), kg/m227.6 (4.1)27.5 (3.9)27.7 (4.3).704
Smokers, n (%)123 (27.5)90 (44.8)33 (13.4)<.001
Ex-smokers <1 y, n (%)20 (4.5)16 (8.0)4 (1.6)<.01
GFR estimated by MDRD equation, mean (SD), mL/min/1.73 m276.8 (14.5)80.9 (15.9)73.4 (12.3)<.001
GFR estimated by Cockcroft-Gault formula, mean (SD), mL/min/1.73m286.4 (21.2)93.4 (21.2)80.9 (19.5)<.001
Patients with GFR <60 mL/min/1.73 m2 by MDRD equation, n (%)30 (6.7)8 (4.0)22 (8.9)<.05
Patients with GFR <60 mL/min/1.73 m2 by Cockcroft-Gault formula, n (%)28 (6.3)9 (4.5)19 (7.7).158
Risk estimated by original Framingham function, mean (SD), %11.616.27.8<.01
Risk estimated by REGICOR Framingham function, mean (SD), %4.35.73.3.246
Coronary events, n (%)b30 (6.7)22 (10.9)8 (3.3)<.01

  • BMI = body mass index; DBP = diastolic blood pressure; GFR = glomerular filtration rate; HDL = high-density lipoprotein; LDL=low-density lipoprotein; MDRD=Modification of Diet in Renal Disease; SBP = systolic blood pressure.

  • ↵a Median of quartile 1–quartile 3, nonnormal distribution.

  • ↵b Events during 10-year follow-up.