Characteristics of Patients Identified as of High Risk by the Original and REGICOR Framingham Functions
| Characteristic | High Risk by Original Framingham (n=66) | High Risk by REGICOR Framingham (n=31) |
|---|---|---|
| Age, mean (SD), y | 59.2 (8.6) | 61.6 (7.1) |
| SBP, mean (SD), mm Hg | 142.1 (15.7) | 142.2 (11.5) |
| DBP, mean (SD), mm Hg | 86.6 (10.4) | 86.1 (7.6) |
| Total cholesterol, mean (SD), mg/dL | 252.1 (32.7) | 255.2 (30.5) |
| HDL cholesterol, mean (SD), mg/dL | 42.3 (12.9) | 40.2 (13.4) |
| LDL cholesterol, mean (SD), mg/dL | 157.7 (32.0) | 182.1 (33.7) |
| Triglycerides, median (SD), mg/dLa | 145.0 (105.0–206.8) | 139.0 (106.0–205.0) |
| BMI, mean (SD), kg/m2 | 28.7 (4.4) | 28.7 (3.8) |
| Smokers, n (%) | 34 (51.5) | 17 (54.8) |
| Ex-smokers <1 y, n (%) | 10 (15.2) | 5 (16.1) |
| Arterial hypertension, n (%) | 25 (37.9) | 11 (35.5) |
| GFR by MDRD equation, mean (SD), mL/min/1.73 m2 | 75.7 (10.4) | 72.9 (8.8) |
| GFR by Cockcroft-Gault formula, mean (SD), mL/min/1.73 m2 | 85.7 (21.3) | 79.9 (16.2) |
| Patients with GFR <60 mL/min/1.73m2 by MDRD equation, n (%) | 3 (4.5) | 2 (6.5) |
| Patients with GFR <60 mL/min/1.73 m2 by Cockcroft-Gault formula, n (%) | 6 (9.1) | 4 (12.9) |
| Coronary events, n (%)b | 10 (15.2) | 5 (16.1) |
| Coronary risk estimated by original Framingham function, % (?) | 28.5 (7.9) | 34.2 (8.1) |
| Cardiovascular risk estimated by REGICOR Framingham function, % (?) | 10.6 (3.4) | 13.1 (3.6) |
| Men, n (%) | 59 (89.4) | 27 (87.1) |
BMI = body mass index; DBP = diastolic blood pressure; GFR = glomerular filtration rate; HDL=high-density lipoprotein; LDL=low-density lipoprotein; MDRD=Modification of Diet in Renal Disease; SBP = systolic blood pressure.
↵a Median of quartile 1–quartile 3, nonnormal distribution.
↵b Events during 10-year follow-up.