Hazard Ratios for Major Depression for Time to an Hypoglycemic Event or for Relative Risk for Number of Hypoglycemic Events (N=4,117)
| Covariate Adjustment | Time to Hypoglycemic Event HR (95% CI) | Number of Hypoglycemic Events RR (95% CI) |
|---|---|---|
| Unadjusted | 1.89 (1.39–2.56) | 1.91 (1.49–2.43) |
| Adjusted | ||
| Prior hypogycemic eventa | 1.65 (1.21–2.25) | 1.69 (1.32–2.17) |
| Prior hypogycemic eventa and demographic characteristicsb | 1.78 (1.30–2.44) | 1.76 (1.37–2.26) |
| Prior hypogycemic eventa and demographicb and clinicalc characteristics | 1.41 (1.03–1.94) | 1.39 (1.08–1.80) |
| Prior hypogycemic eventa and demographic,b clinical,c and health risk behaviord characteristics | 1.42 (1.03–1.96) | 1.34 (1.03–1.74) |
HR=hazard ratio; RR=relative risk.
↵a At least 1 hypoglycemic event in the 5 years before entering study.
↵b Demographic characteristics: age, sex, race (white vs nonwhite race/ethnicity), education (some college, high school, or less), and marital status (married or partnered, single).
↵c Clinical characteristics: diabetes duration, insulin use, RxRisk score, hypertension diagnosis, diabetes type 1 or 2, and diabetes complication score.
↵d Health risk behavior characteristics: body mass index, current smoking, and physical activity.