Table 5

Change in Knee Pain Scale Pain Frequency and Pain Severity Scores in Individual Treated Knees Over Time

MeasureWeek 5Week 9Week 12Week 24Week 52
KPS pain frequency score, mean (SE) [No.]
 Dextrose−0.55 (0.26) [43]−0.84a (0.25) [42]−0.87a (0.27) [38]−1.19a (0.25) [40]−1.20a (0.21) [37]
 Saline−0.26 (0.26) [40]−0.32 (0.25) [37]−0.31 (0.27) [36]−0.48 (0.25) [37]−0.60 (0.21) [38]
 Exercise−0.15 (0.25) [38]−0.22 (0.24) [40]−0.12 (0.26) [37]−0.49 (0.24) [39]−0.40 (0.21) [38]
KPS pain severity score, mean (SE)
 Dextrose−0.25 (0.26)−0.48 (0.25)−0.51 (0.27)−0.92a (0.25)−0.92a (0.21)
 Saline−0.07 (0.26)−0.19 (0.25)−0.16 (0.27)−0.26 (0.25)−0.32 (0.21)
 Exercise−0.07 (0.25)−0.15 (0.24)−0.06 (0.26)−0.33 (0.24)−0.11 (0.21)
  • KPS=knee pain scale.

  • Repeated measures analysis of variance compared between-group KPS scores after adjusting for baseline scores, age, sex, and body mass index.

  • a Change in dextrose score was greater than change in saline (P <.05) and exercise (P <.05) scores, and there were no statistically significant differences between saline and exercise scores.