Unadjusted, Age-Adjusted, and Multivariable-Adjusted Odds Ratios of the Association Between Pregnancy Loss and Risk of Total Coronary Heart Disease
| Pregnancy Loss | Events No. | Unadjusted OR (95% CI) | Age Adjusted OR (95% CI) | Multivariable Adjusteda OR (95% CI) |
|---|---|---|---|---|
| Miscarriage | ||||
| 0 | 1,868 | 1.00 | 1.00 | 1.00 |
| 1 | 746 | 1.26 (1.15–1.37) | 1.23 (1.13–1.35) | 1.19 (1.08–1.32) |
| ≥2 | 408 | 1.37 (1.23–1.53) | 1.31 (1.17–1.46) | 1.18 (1.04–1.34) |
| Stillbirth | ||||
| 0 | 2,809 | 1.00 | 1.00 | 1.00 |
| ≥1 | 179 | 1.43 (1.22–1.43) | 1.36 (1.16–1.59) | 1.27 (1.07–1.51) |
OR = odds ratio; ACE = angiotensin-converting enzyme inhibitor; ARB = angiotensin receptor blocker.
↵a Adjusted for: age, race, education, income, smoking status, marital status, gravidity, family history of myocardial infarction, hypertension, history of diabetes, history of lipid disorder, body mass index, waist-to-hip ratio, aspirin use, diuretic use, ACE inhibitor/ARB use, calcium channel blocker use, alcohol use, depression, physical activity, and white blood cell count.